ArticleJournal of neurosurgery. Case lessons2024
The Pipeline embolization device for the treatment of intracranial aneurysms in pediatric patients with tuberous sclerosis complex: illustrative cases.
Article in Journal of neurosurgery. Case lessons, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Combined Pipeline Embolization and Coiling of an Intracranial Aneurysm in Marfan Syndrome: A Case Report and Literature Review.Neurosurgery practice · 2025Article
- Cranial bypass for occlusive carotid dissection in osteogenesis imperfecta: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Pipeline embolization in patients with hemoglobinopathies: A cohort study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
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Authors and funding
7 authors.
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Abstract
backgroundTuberous sclerosis complex (TSC) is a neurocutaneous disorder characterized by the multisystem development of benign tumors. Patients with TSC are also at an increased risk of developing intracranial aneurysms early in life. While aneurysms have historically been treated with open surgical clipping, endovascular approaches are increasingly being used in both pediatric and adult populations. OBSERVATIONS: In this case series, the authors report the endovascular treatment of three young patients with TSC and fusiform intracranial aneurysms using the Pipeline embolization device (PED) for flow diversion of the affected artery. In all cases, complete aneurysm occlusion was observed, with good parent artery wall reconstruction and no parent artery stenosis or occlusion. All flow diverter stents were deployed successfully, and there were no device-related complications. All patients were maintained on dual antiplatelet therapy. LESSONS: The PED can serve as a safe and effective endovascular alternative to open surgery for the treatment of intracranial aneurysms in young patients with TSC. This could avoid an additional craniotomy in a population already likely to require surgical intervention for TSC-related tumors or epilepsy. Further studies investigating the use of the PED in the pediatric population must be undertaken to validate its long-term efficacy. https://thejns.org/doi/10.3171/CASE24452.
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