ArticleJournal of neurosurgery. Case lessons2024
Treatment of cerebral radiation necrosis using hyperbaric oxygen therapy in a child: illustrative case.
Article in Journal of neurosurgery. Case lessons, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Radiation-Induced Brain Injury: Mechanistic Insights and the Promise of Gut-Brain Axis Therapies.Brain sciences · 2024Review
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundCerebral radiation necrosis (RN) is an uncommon sequela that occurs in up to 25% of irradiated patients. This can occur 6 months to several years after therapy and create symptoms of headaches, focal neurological deficits, seizures, or behavioral changes. Management can involve corticosteroids, antiplatelet drugs, surgery, and hyperbaric oxygen therapy (HBOT). Currently, there is a paucity of literature investigating these therapies for routine use in the pediatric population. OBSERVATIONS: A 5-year-old male with a right frontal atypical teratoid rhabdoid tumor previously underwent craniotomy for tumor resection, followed by chemotherapy, radiation, and autologous stem cell transplant therapy. Progressive radiographic changes surrounding the resection cavity were noted on routine surveillance imaging 20 months after the initial craniotomy and 11 months after the completion of radiation therapy. A biopsy ultimately confirmed RN. Due to the patient's previous complications with steroid use, the patient underwent HBOT. This achieved a significant improvement in clinical and radiographic sequelae of RN. LESSONS: HBOT was utilized successfully for the management of this patient's RN. HBOT should be considered for pediatric patients with cerebral RN as a potential treatment strategy. https://thejns.org/doi/10.3171/CASE24460.
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