Evidence map›Paper›PMID 39556733›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Symmetry engineering in 2D bioelectronics facilitating augmented biosensing interfaces.

Yizhang Wu, Yihan Liu, Yuan Li, Ziquan Wei, Sicheng Xing, Yunlang Wang, Dashuai Zhu, Ziheng Guo, Anran Zhang, Gongkai Yuan and 6 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yizhang Wu *Department of Applied Physical Sciences, University of North Carolina, Chapel Hill, NC 27599.ORCID 0000-0001-6244-8458
Yihan Liu *Department of Applied Physical Sciences, University of North Carolina, Chapel Hill, NC 27599.ORCID 0000-0003-3671-9191
Yuan Li *Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.ORCID 0000-0002-1929-5465
Ziquan WeiDepartment of Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.ORCID 0000-0001-6553-4482
Sicheng XingDepartment of Applied Physical Sciences, University of North Carolina, Chapel Hill, NC 27599.
Yunlang WangDepartment of Physics, Nanjing University, Nanjing, Jiangsu 210000, China.
Dashuai ZhuDepartment of Biomedical Engineering, Columbia University, New York, NY 10027.ORCID 0000-0002-4645-5786
Ziheng GuoDepartment of Applied Physical Sciences, University of North Carolina, Chapel Hill, NC 27599.
Anran ZhangDepartment of Applied Physical Sciences, University of North Carolina, Chapel Hill, NC 27599.ORCID 0009-0008-8442-2695
Gongkai YuanDepartment of Applied Physical Sciences, University of North Carolina, Chapel Hill, NC 27599.
Zhibo ZhangDepartment of Computer Science and Engineering, Michigan State University, East Lansing, MI 48824.
Ke HuangDepartment of Molecular Biomedical Sciences, North Carolina State University, Raleigh, NC 27607.ORCID 0000-0002-9355-7224
Yong WangDepartment of Physics, Nanjing University, Nanjing, Jiangsu 210000, China.ORCID 0000-0001-5085-5312
Guorong WuDepartment of Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Ke ChengDepartment of Biomedical Engineering, Columbia University, New York, NY 10027.
Wubin BaiDepartment of Applied Physical Sciences, University of North Carolina, Chapel Hill, NC 27599.ORCID 0000-0003-2872-5559

Funding

Wearable, Wireless Deep-tissue Sensing Patch for Continuous Monitoring of Recovery from Microsurgical Tissue TransferR01EB034332 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Wubin Bai · 2023 to 2026
$1.3M
HHS | NIH | National Institute of Biomedical Imaging and Bioengineering (NIBIB) 1R01EB034332-01National Science Foundation (NSF) ECCS-2139659NIBIB NIH HHS R01 EB034332
6 · The paper itself

Abstract

Symmetry lies at the heart of two-dimensional (2D) bioelectronics, determining material properties at the fundamental level. Breaking the symmetry allows emergent functionalities and effects. However, symmetry modulation in 2D bioelectronics and the resultant applications have been largely overlooked. Here, we devise an oxidized architectural MXene, referred to as oxidized MXene (OXene), that couples orbit symmetric breaking with inverse symmetric breaking to entitle the optimized interfacial impedance and Schottky-induced piezoelectric effects. The resulting OXene validates applications ranging from microelectrode arrays, gait analysis, active transistor matrix, and wireless signaling transmission, which enables high-fidelity signal transmission and reconfigurable logic gates. Furthermore, OXene interfaces were investigated in both rodent and porcine myocardium, featuring high-quality and spatiotemporally resolved physiological recordings, while accurate differentiated predictions, enabled via various machine learning pipelines.

Indexed as

Biosensing TechniquesAnimalsMiceMicroelectrodesRatsSwinebioelectronicsbiosensinglogic matrixmachine learningsymmetry engineering

Identifiers

PMID39556733
PMCPMC11621509

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.