Evidence map›Paper›PMID 39556691›Full record

ReviewJournal of applied clinical medical physics2025

Machine learning in image-based outcome prediction after radiotherapy: A review.

Xiaohan Yuan, Chaoqiong Ma, Mingzhe Hu, Richard L J Qiu, Elahheh Salari, Reema Martini, Xiaofeng Yang

Abstract readReview
In one paragraph

Review in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Cancer Pain: Radiotherapy as a Double-Edged Sword.International journal of molecular sciences · 2025
    Review
  9. Uncertainties in outcome modelling in radiation oncology.Physics and imaging in radiation oncology · 2025
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaohan YuanDepartment of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, Georgia, USA.
Chaoqiong MaDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
Mingzhe HuDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
Richard L J QiuDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
Elahheh SalariDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
Reema MartiniEmory School of Medicine, Emory University, Atlanta, Georgia, USA.
Xiaofeng YangDepartment of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, Georgia, USA.

Funding

Translational and Clinical Trial Correlates CoreU54CA274513 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI Timothy An-thy Chan · 2022 to 2026
$9.3M
Real-time Volumetric Imaging for Motion Management and Dose Delivery VerificationR01CA272991 · NCI · EMORY UNIVERSITY · PI Zhen Tian, Xiaofeng Yang · 2023 to 2026
$2.3M
Intelligent and Personalized Online Adaptive Proton TherapyR01DE033512 · NIDCR · UNIVERSITY OF CHICAGO · PI Zhen Tian, Xiaofeng Yang · 2024 to 2026
$1.8M
Artificial Intelligence Driven Platform for PET/MR ImagingR56EB033332 · NIBIB · EMORY UNIVERSITY · PI MAO, HUI, YANG, XIAOFENG · 2022 to 2022
$764k
NCI NIH HHS R01 CA272991NCI NIH HHS U54 CA274513NIBIB NIH HHS R56 EB033332NIDCR NIH HHS R01 DE033512NIH HHS R01CA272991NIH HHS R01DE033512NIH HHS R56EB033332NIH HHS U54CA274513
6 · The paper itself

Abstract

The integration of machine learning (ML) with radiotherapy has emerged as a pivotal innovation in outcome prediction, bringing novel insights amid unique challenges. This review comprehensively examines the current scope of ML applications in various treatment contexts, focusing on treatment outcomes such as patient survival, disease recurrence, and treatment-induced toxicity. It emphasizes the ascending trajectory of research efforts and the prominence of survival analysis as a clinical priority. We analyze the use of several common medical imaging modalities in conjunction with clinical data, highlighting the advantages and complexities inherent in this approach. The research reflects a commitment to advancing patient-centered care, advocating for expanded research on abdominal and pancreatic cancers. While data collection, patient privacy, standardization, and interpretability present significant challenges, leveraging ML in radiotherapy holds remarkable promise for elevating precision medicine and improving patient care outcomes.

Indexed as

Machine LearningNeoplasmsHumansImage Processing, Computer-AssistedRadiotherapy DosageRadiotherapy Planning, Computer-Assistedcancer radiotherapymachine learningmedical imagingoutcome prediction

Identifiers

PMID39556691
PMCPMC11712300

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.