Evidence map›Paper›PMID 39556419›Full record

ArticleMicrobial genomics2024

Evolution of the CRISPR-Cas9 defence system in

Thomas Ipoutcha, Iason Tsarmpopoulos, Géraldine Gourgues, Vincent Baby, Paul Dubos, Geoffrey E Hill, Yonathan Arfi, Carole Lartigue, Patricia Thébault, Camille Bonneaud and 1 more

Abstract read
In one paragraph

Article in Microbial genomics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Pathogenic mechanisms and vaccine development forFrontiers in microbiology · 2025
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Thomas IpoutchaUniv. Bordeaux, INRAE, UMR BFP, F-33882, Villenave d'Ornon, France.
Iason TsarmpopoulosUniv. Bordeaux, INRAE, UMR BFP, F-33882, Villenave d'Ornon, France.
Géraldine GourguesUniv. Bordeaux, INRAE, UMR BFP, F-33882, Villenave d'Ornon, France.
Vincent BabyUniv. Bordeaux, INRAE, UMR BFP, F-33882, Villenave d'Ornon, France.
Paul DubosUniv. Bordeaux, INRAE, UMR BFP, F-33882, Villenave d'Ornon, France.
Geoffrey E HillDepartment of Biological Sciences, Auburn University, Auburn, Alabama, 36849-5414, USA.
Yonathan ArfiUniv. Bordeaux, INRAE, UMR BFP, F-33882, Villenave d'Ornon, France.
Carole LartigueUniv. Bordeaux, INRAE, UMR BFP, F-33882, Villenave d'Ornon, France.
Patricia ThébaultUniv. Bordeaux, CNRS, Bordeaux INP, LaBRI, UMR 5800, F-33400 Talence, France.
Camille BonneaudCentre for Ecology and Conservation, University of Exeter, Penryn TR10 9FE, UK.
Pascal Sirand-PugnetUniv. Bordeaux, INRAE, UMR BFP, F-33882, Villenave d'Ornon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clustered regularly interspaced short palindromic repeat (CRISPR)-Cas systems are bacterial defences that target bacteriophages and mobile genetic elements. How these defences evolve in novel host environments remains largely unknown. We studied the evolution of the CRISPR-Cas system in

Indexed as

CRISPR-Cas SystemsEvolution, MolecularMycoplasma gallisepticumAnimalsBacteriophagesPhylogenybird pathogenCRISPR-Casevolutionhost shiftmycoplasma

Identifiers

PMID39556419
PMCPMC11893278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.