Article in American journal of respiratory cell and molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
12 authors.
Qing LiState Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot, China.ORCID 0000-0002-3717-8668
Junwei ZengState Key Laboratory of Genetic Engineering, School of Life Sciences, Greater Bay Area Institute of Precision Medicine (Guangzhou), Zhongshan Hospital, Fudan University, Shanghai, China.
Silu HuDepartment of Respiratory and Critical Care Medicine, State Key Laboratory of Respiratory Health and Multimorbidity and.
Chunjie LiDepartment of Respiratory and Critical Care Medicine, State Key Laboratory of Respiratory Health and Multimorbidity and.
Jeffrey A WhitsettDivision of Pulmonary Biology and.
Yi ZhengDivision of Experimental Hematology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Fengming LuoDepartment of Respiratory and Critical Care Medicine, State Key Laboratory of Respiratory Health and Multimorbidity and.
Chang XuDepartment of Pediatric Surgery, West China Hospital, Sichuan University, Chengdu, China.
Taozhen HeDepartment of Pediatric Surgery, West China Hospital, Sichuan University, Chengdu, China.
Xinhua LinState Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot, China.
Huajing WanDepartment of Respiratory and Critical Care Medicine, State Key Laboratory of Respiratory Health and Multimorbidity and.ORCID 0000-0003-0366-1499
Funding
Airway Progenitor Cell Profileration and Differentiation During Lung RepairU01HL110964 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI STREETER, PHILIP R, WHITSETT, JEFFREY A · 2012 to 2016
$3.3M
National Science Foundation of China NSFC32192400National Science Foundation of China NSFC32271542National Science Foundation of China NSFC81270057NHLBI NIH HHS U01 HL110964NHLBI NIH HHS U01-HL110964
6 · The paper itself
Abstract
Tubulogenesis depends on precise cell shape changes driven by asymmetric tension from the actin cytoskeleton. How actin asymmetry is dynamically controlled to coordinate epithelial cell shape changes required for respiratory tubulogenesis remains unknown. Herein, we unveiled a critical role for the transcription factor KLF5, regulating actin asymmetry, inducing epithelial cell shape changes by balancing RHOA and CDC42 GTPase activity via RICH2. Conditional
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
KLF5 Shapes Developing Respiratory Tubules by Inhibiting Actin Asymmetry in Epithelial Cells. · full record | OpenQuestion