ArticlePediatric nephrology (Berlin, Germany)2025
Utility of shear wave elastography in evaluation of children with chronic kidney disease.
Article in Pediatric nephrology (Berlin, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Shear wave elastography for the evaluation of children with chronic kidney disease: promising, but insufficient.Pediatric nephrology (Berlin, Germany) · 2025Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundShear wave elastography (SWE) is proven for liver fibrosis. However, there are challenges in assessing the kidney owing to its surrounding structures, retroperitoneal location, and visceral fat. Kidney biopsy is the gold standard for estimating fibrosis, but is associated with inherent risks of bleeding and sedation. This study explores SWE's potential in assessing kidney fibrosis in CKD.
methodsA total of 160 children < 18 years old with CKD or those undergoing kidney biopsy were enrolled from June 2022 to June 2024 in a cross-sectional study. SWE on a Philips Epic Elite system provided Young's modulus (YM) values. We analysed SWE with estimated glomerular filtration rate (eGFR, (CKD stages)) and urine protein creatinine ratio, in patients with CKD. Forty-one patients who underwent kidney biopsy were assessed for interstitial fibrosis and tubular atrophy (IFTA) and SWE.
resultsThere was no relation between CKD stages, GFR, or proteinuria with YM/SWE. YM/SWE poorly predicted CKD with eGFR < 60 ml/min/1.73 m
conclusionsSWE was limited in differentiating CKD stages but could predict fibrosis over 50%. SWE might be helpful in identifying increasing fibrosis, but it is not useful in detecting early fibrosis or chronicity.
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