Evidence map›Paper›PMID 39555983›Full record

ArticleEuropean journal of translational myology2024

Efficacy of electrical stimulation of the zygomaticus muscle in complete facial paralysis: evidence from facial grading and automated image analysis.

Johannes Krauß, Gabriel Meincke, Maren Geitner, Anna-Maria Kuttenreich, Jan Beckmann, Dirk Arnold, Jonas Ballmaier, Thomas Lehmann, Winfried Mayr, Orlando Guntinas-Lichius and 1 more

Abstract read
In one paragraph

Article in European journal of translational myology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Johannes KraußENT-Department, Jena University Hospital, Jena. johannes.krauss@uni-jena.de.
Gabriel MeinckeENT-Department, Jena University Hospital, Jena. gabriel.meincke@uni-jena.de.
Maren GeitnerENT-Department, Jena University Hospital, Jena, Germany; Facial-Nerve-Center, Jena University Hospital, Jena. maren.geitner@med.uni-jena.de.
Anna-Maria KuttenreichENT-Department, Jena University Hospital, Jena, Germany; Facial-Nerve-Center, Jena University Hospital, Jena. anna.kuttenreich@rwth-aachen.de.
Jan BeckmannENT-Department, Jena University Hospital, Jena. j-beckmann1996@web.de.
Dirk ArnoldENT-Department, Jena University Hospital, Jena, Germany; Facial-Nerve-Center, Jena University Hospital, Jena. Dirk.Arnold@med.uni-jena.de.
Jonas BallmaierENT-Department, Jena University Hospital, Jena, Germany; Facial-Nerve-Center, Jena University Hospital, Jena. Jonas.Ballmaier@med.uni-jena.de.
Thomas LehmannInstitute for Medical Statistics, Computer Science and Data Science, Jena University Hospital, Jena. thomas.lehmann@med.uni-jena.de.
Winfried MayrCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna. Winfried.Mayr@meduniwien.ac.at.
Orlando Guntinas-LichiusENT-Department, Jena University Hospital, Jena, Germany; Facial-Nerve-Center, Jena University Hospital, Jena, Germany; Center of Rare Diseases, Jena University Hospital, Jena. Orlando.Guntinas@med.uni-jena.de.
Gerd Fabian VolkENT-Department, Jena University Hospital, Jena, Germany; Facial-Nerve-Center, Jena University Hospital, Jena, Germany; Center of Rare Diseases, Jena University Hospital, Jena. fabian.volk@med.uni-jena.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surface Functional Electrical Stimulation (FES) is a well-studied intervention for multiple muscular disorders. However, it is still controversially discussed as a complementary therapy for complete facial paralysis. The aim of this intervention is to test a daily home-based ES concept as a pilot study regarding safety, feasibility, and effects on facial functionality and symmetry. In a prospective single-centre pilot study, 10 patients (median 61 years, denervation 130 d) with complete peripheral facial paralysis performed home-based FES of the affected lateral mouth region Stimulation parameters, facial paralysis scores and standardised photographs were assessed in monthly follow-ups. No serious adverse events appeared. Stimulation parameters could be constantly increased indicating effective muscle training while subjectively perceived functionality of the face improved. Thus, smile angle of the paralysed side improved as well. FES is a safe therapy model for application in facial nerve paralysis patients. A feasible stimulation protocol could be applied, which improved the functionality and symmetry of the stimulated facial region. A future controlled, randomised and double-blind follow-up study is needed to investigate these initial results in a further evolved replicable setting.

Identifiers

PMID39555983
PMCPMC11726304

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.