Evidence map›Paper›PMID 39555917›Full record

ArticleMicrobiology spectrum2025

High level non-carbapenemase carbapenem resistance by overlaying mutations of

Yan Yang, Xue Li, Lang Sun, Xiu-Kun Wang, You-Wen Zhang, Jing Pang, Guo-Qing Li, Xin-Xin Hu, Tong-Ying Nie, Xin-Yi Yang and 4 more

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Multifaceted effects ofVirulence · 2026
    Article
  2. Targeting Outer Membrane Vesicles ofJournal of microbiology and biotechnology · 2026
    Review
  3. Article
  4. Article
  5. Identification of a novel gene inAntimicrobial agents and chemotherapy · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Specific variants inMicrobiology spectrum · 2025
    Article
  14. Article
  15. Resistance mechanisms and therapeutic strategies forTherapeutic advances in infectious disease
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yan YangBeijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.ORCID 0000-0001-5369-2459
Xue LiBeijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Lang SunBeijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Xiu-Kun WangBeijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
You-Wen ZhangBeijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.ORCID 0000-0002-3985-1393
Jing PangBeijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.ORCID 0000-0002-0538-0327
Guo-Qing LiBeijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Xin-Xin HuBeijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Tong-Ying NieBeijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Xin-Yi YangBeijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Jian-Hua Liu *Department of Respiratory Medicine, the First Affiliated Hospital of Hebei North University, Zhangjiakou, China.
Gerrit Brandis *Department of Cell and Molecular Biology (ICM), Uppsala University, Uppsala, Sweden.
Xue-Fu You *Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Cong-Ran Li *Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.ORCID 0000-0002-7505-7525

Funding

MOST | National Natural Science Foundation of China (NSFC) 82273980MOST | National Natural Science Foundation of China (NSFC) 82330110, 32141003the CAMS Innovation Fund for Medical Sciences 2021-I2M-1-030the CAMS Innovation Fund for Medical Sciences 2021-I2M-1-039the National Mega-project for Innovative Drugs 2019ZX09721001the National Science and Technology Infrastructure of China NPRC-32
6 · The paper itself

Abstract

Carbapenem-resistant IMPORTANCE: The emergence of carbapenem-resistant

Indexed as

Anti-Bacterial AgentsBacterial ProteinsCarbapenemsMicrobial Sensitivity TestsPorinsPseudomonas aeruginosaBacterial Outer Membrane Proteinsbeta-LactamasesDrug Resistance, BacterialHumansMembrane Transport ProteinsMeropenemMutationPseudomonas InfectionsRepressor ProteinsAnti-Bacterial AgentsBacterial Outer Membrane ProteinsBacterial Proteinsbeta-LactamasescarbapenemaseCarbapenemsMembrane Transport ProteinsMeropenemMexR protein, Pseudomonas aeruginosaOprD protein, Pseudomonas aeruginosaPorinsRepressor Proteinscarbapenem resistancein vivo evolutionoverlaying point mutationPseudomonas aeruginosa

Identifiers

PMID39555917
PMCPMC11705820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.