ArticleImmunity, inflammation and disease2024
The Complex Relationship Between Chronic Obstructive Pulmonary Disease With Cardiovascular Disease and Their Interactions With COVID-19 Vaccination: A Retrospective Study.
Article in Immunity, inflammation and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Multi-Ancestry Mendelian Randomization Reveals Lipid-Associated Genetic Risk Factors for COPD.International journal of chronic obstructive pulmonary disease · 2025Pooled it
- The Effect of Heated, Humidified High-Flow Air in COPD Patients With Chronic Bronchitis.Pulmonary medicine · 2025Trial
- Associations between environmental exposure, lifestyle, and the risk of respiratory infections among 67890 adults: A population-based cohort analysis using UK Biobank data.Global health research and policy · 2026Article
- Socio-Ecological Factors Influencing Maternal and Child Health Outcomes During Floods in South Punjab Pakistan 2025: A Mixed-Methods Approach.Health expectations : an international journal of public participation in health care and health policy · 2026Article
- The Impact of COVID-19 on Obstructive Pulmonary Diseases: A Narrative Review of Long-Term Consequences and Vaccination Strategies.Health science reports · 2026Article
- Real-time assessment of exercise rehabilitation and symptoms in hospitalized COPD patients.Frontiers in medicine · 2026Article
- Multidimensional Impact of Smog on Respiratory and Ocular Health: A Cross-Sectional Study With Socio-Psychological and Public Health Prospective.Health science reports · 2025Article
- Long-Term Effects of COVID-19 on Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2025Article
- Risk Factors for Acute Exacerbation in Patients with COPD Group E in Ningbo: Risk Analysis of Irregular Review, Cardiovascular Complications, and Lung Function Decline.International journal of chronic obstructive pulmonary disease · 2025Article
- Chronic Obstructive Pulmonary Disease Patients With Community-Acquired Pneumonia on Inhaled Corticosteroid Therapy: A Comprehensive Analysis of Risk Factors, Disease Burden, and Prevention Strategies.Health science reports · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundPreviously, most researchers explored the association between chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD). This study investigates the distinct influence of COVID-19 vaccination status on patients with both conditions.
objectiveWe investigate the relationship between COPD and CVD in a cohort of 838 individuals who presented with both conditions. Our aim is to understand how these conditions interact and how COVID-19 vaccination status affects patient outcomes.
methodsA retrospective analysis was conducted on 838 patients with COPD and CVD treated at DHQ Hospital in Muzaffargarh, Punjab, Pakistan, from November 2022 to April 2023. We employed multiple logistic regression and the Wilcoxon signed-rank test to assess the odds ratio and relative risk of COPD in patients with-CVD under various conditions. Additionally, we analyzed time-to-death and survival using Kaplan-Meier methods.
resultsFindings reveal a 7.95 times higher risk of death in patients without COVID-19 vaccination compared with those who were vaccinated (95% CI, 6.12-10.33). Conversely, COVID-19-vaccinated patients exhibited a 0.221 times lower risk of recovery than their nonvaccinated counterparts (95% CI, 0.08-0.60). We also observed significant differences in time-to-death and recovery based on the presence of COPD and CVD, with vaccinated patients generally experiencing milder disease.
conclusionOur study assessed the impact of COVID-19 vaccination status on patient outcomes in patients with overlapping COPD and CVD. Individuals diagnosed with COPD and CVD display significant differences in terms of their probability of survival, with those who have received vaccinations.
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