Evidence map›Paper›PMID 39555577›Full record

ReviewFuture medicinal chemistry2024

Unveiling the potential of HS-1793: a review of its anticancer properties and therapeutic promise.

Xavier Capó, Manuel Jiménez-Garcia, Farukh Sharopov, Patrick Valere Tsouh Fokou, Miquel Martorell, Afaf Ahmed Aldahish, Raffaele Pezzani, Javad Sharifi-Rad, Daniela Calina

Abstract readReview
In one paragraph

Review in Future medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Clarifying healthy aging: building a common language for policy innovation within the Age-It Research Program.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
    Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xavier CapóTranslational Research in Aging & Longevity (TRIAL) Group, Health Research Institute of the Balearic Islands (IdISBa), Palma, 07120, Spain.
Manuel Jiménez-GarciaLaboratory of Neurophysiology, Biology Department, University of Balearic Islands (UIB), Palma de Mallorca, Spain.
Farukh SharopovResearch Institution "Chinese-Tajik Innovation Center for Natural Products" of the National Academy of Sciences of Tajikistan, Dushanbe, Tajikistan.
Patrick Valere Tsouh FokouDepartment of Biochemistry, Faculty of Science, University of Bamenda, 39 Bamenda-Bambili, Cameroon.
Miquel MartorellDepartment of Nutrition & Dietetics, Faculty of Pharmacy & Centre for Healthy Living, University of Concepción, Concepción, Chile.
Afaf Ahmed AldahishDepartment of Pharmacology, College of Pharmacy, King Khalid University, Abha, 61441, Kingdom of Saudi Arabia.
Raffaele PezzaniPhytotherapy Lab, Dept. Medicine (DIMED), University of Padova, via Ospedale 105, Padova, 35128, Italy.
Javad Sharifi-RadUniversidad Espíritu Santo, Samborondón, 092301, Ecuador.ORCID 0000-0002-7301-8151
Daniela CalinaDepartment of Clinical Pharmacy, University of Medicine & Pharmacy of Craiova, Craiova, 200349, Romania.ORCID 0000-0002-1523-9116

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HS-1793 is a novel derivative of resveratrol, a compound known for its numerous beneficial effects, including anticancer activity, anti-inflammatory response, antimicrobial, antiaging, anti-cardiovascular disease activity, neuroprotective activity, etc. Despite its wide and interesting properties, resveratrol suffers from a crucial flaw because it is low bioavailable. For this reason, many other derivatives were explored and among them, HS-1793 has caught the attention of researchers. HS-1793 is a synthetic derivative of resveratrol discovered in 2007 that has been shown to have anti-cancer and anti-inflammatory properties. In addition, the compound showed a positive profile in metabolic processes, with adequate pharmacokinetics and pharmacodynamics. This review highlights current research on HS-1793, evaluating

Indexed as

Antineoplastic AgentsNaphtholsNeoplasmsResorcinolsAnimalsAnti-Inflammatory AgentsHumans4-(6-hydroxy-2-naphthyl)-1,3-benzenediolAnti-Inflammatory AgentsAntineoplastic AgentsNaphtholsResorcinolsanticancerbioavailabilitycell modelsHS-1793preclinicalresveratrol

Identifiers

PMID39555577
PMCPMC11622770

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.