Evidence map›Paper›PMID 39555576›Full record

ArticleFuture oncology (London, England)2024

Testosterone recovery post discontinuation of androgen deprivation for the treatment of advanced prostate cancer.

Neal D Shore, Alicia K Morgans, Ronald F Tutrone

Abstract read
In one paragraph

Article in Future oncology (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Neal D ShoreCPI - Carolina Urologic Research Center, Myrtle Beach, SC 29572, USA.ORCID 0000-0001-5767-0548
Alicia K MorgansDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.ORCID 0000-0002-6563-4587
Ronald F TutroneDivision of Urology, Chesapeake Urology, Towson, MD 21204, USA.

Funding

Pfizer Inc.Sumitomo Pharma Switzerland GmbH
6 · The paper itself

Abstract

While suppressing testosterone to castration levels is the aim of androgen deprivation therapy for the treatment of advanced prostate cancer, studies have shown that prolonged low testosterone levels can have negative effects on patients' overall health and quality of life. This podcast covers two recently published papers that examined testosterone recovery in different ways. One real-world study assessed the impact of delayed testosterone recovery on clinical outcomes in patients with prostate cancer. A second subgroup analysis of the HERO trial assessed rates of testosterone recovery in patients receiving the long-acting, injectable gonadotropin-releasing hormone receptor agonist, leuprolide or the oral, once-daily gonadotropin-releasing hormone receptor antagonist, relugolix.

Indexed as

Androgen AntagonistsAntineoplastic Agents, HormonalProstatic NeoplasmsTestosteroneGonadotropin-Releasing HormoneHumansLeuprolideMaleNeoplasm StagingPhenylurea CompoundsPyrimidinonesQuality of LifeTreatment OutcomeAndrogen AntagonistsAntineoplastic Agents, HormonalGonadotropin-Releasing HormoneLeuprolidePhenylurea CompoundsPyrimidinonesrelugolixTestosteroneadvanced prostate cancerandrogen deprivation therapyGnRH agonists or antagonistspodcasttestosterone recovery

Identifiers

PMID39555576
PMCPMC11721869

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.