Evidence map›Paper›PMID 39555482›Full record

SynthesisFrontiers in neurology2024

Acupuncture in the treatment of chemotherapy-induced peripheral neuropathy: a meta-analysis and data mining.

Limeng Li, Yingxue Huang, Chengfei An, Ning Jing, Chuhan Xu, Xiaoyu Wang, Huanan Li, Tao Tan

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06834685 (Evaluating Laser Photobiomodulation for the Treatment of Neuropathic Pain in Chemotherapy-induced Peripheral Neuropathy), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06834685 narecruitingnot on this mapstarted 2025, after this paper: background citation

Evaluating Laser Photobiomodulation for the Treatment of Neuropathic Pain in Chemotherapy-induced Peripheral Neuropathy: a Randomized, Non-comparative, Placebo-controlled, Single-blinded, Phase II Clinical Trial in Cancer Patients

TypeinterventionalSponsorInstitut du Cancer de Montpellier - Val d'AurelleRan2025 to 2028Enrolled70ConditionsCancer Survivors, Peripheral Neuropathic PainArmsPhotobiomodulation sessions
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The effect of hand massage on pain, comfort, and sleep quality in palliative care oncology patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Limeng LiTuina Department, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Yingxue HuangTuina Department, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Chengfei AnTuina Department, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Ning JingTuina Department, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Chuhan XuTuina Department, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Xiaoyu WangTuina Department, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Huanan LiTuina Department, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Tao TanTuina Department, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The efficacy and acupoint selection of acupuncture in treating chemotherapy-induced peripheral neuropathy (CIPN) remain controversial. This study aims to explore the specific efficacy and acupoint selection of acupuncture in treating CIPN through a meta-analysis and data mining. Methods: Searching for clinical trials on acupuncture treatment for CIPN in 8 databases, evaluating its efficacy and safety through a meta-analysis, and exploring its acupoint selection through data mining. Results: The meta-analysis included 21 studies and 2,121 patients, showing that compared with the control group, the acupuncture group could significantly improve neuropathic pain intensity (SMD = -0.66, 95% CI [-1.07, -0.25], Conclusion: Acupuncture can improve the neuropathic pain intensity, the intensity of the CIPN, MCV of the median nerve, SCV of the tibial nerve and peroneal nerve, quality of life, and has good safety in CIPN patients. LI4 (Hegu), ST36 (Zusanli), LI11 (Quchi), LR3 (Taichong), and SP6 (Sanyinjiao) are the core acupuncture points for treating CIPN, and this protocol has the potential to become a supplementary treatment for CIPN. Systematic review registration: https://www.crd.york.ac.uk/prospero, identifier CRD42024551137.

Indexed as

acupuncturechemotherapy-induced peripheral neuropathycomplementary and alternative therapiesdata miningsystematic review

Identifiers

PMID39555482
PMCPMC11565602

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.