Evidence map›Paper›PMID 39555455›Full record

ReviewFrontiers in oncology2024

Exercise's impact on lung cancer molecular mechanisms: a current overview.

Annamaria Mancini, Francesca Maria Orlandella, Daniela Vitucci, Neila Luciano, Andreina Alfieri, Stefania Orrù, Giuliana Salvatore, Pasqualina Buono

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Annamaria ManciniDepartment of Medical, Human Movement and Well-being Sciences, University Parthenope, Naples, Italy.
Francesca Maria OrlandellaDepartment of Medical, Human Movement and Well-being Sciences, University Parthenope, Naples, Italy.
Daniela VitucciDepartment of Medical, Human Movement and Well-being Sciences, University Parthenope, Naples, Italy.
Neila LucianoDepartment of Advanced Biomedical Sciences, University Federico II, Naples, Italy.
Andreina AlfieriDepartment of Medical, Human Movement and Well-being Sciences, University Parthenope, Naples, Italy.
Stefania OrrùDepartment of Medical, Human Movement and Well-being Sciences, University Parthenope, Naples, Italy.
Giuliana SalvatoreDepartment of Medical, Human Movement and Well-being Sciences, University Parthenope, Naples, Italy.
Pasqualina BuonoDepartment of Medical, Human Movement and Well-being Sciences, University Parthenope, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is the major cause of cancer-related deaths worldwide with an estimated 1.8 million deaths and 2.4 million new cases in 2022. Poor cardiorespiratory fitness, dyspnea and fatigue are the common features in lung cancer patients, partially limiting the exercise prescription. Exercise improves cardiorespiratory and muscular fitness and reduces the risk of some types of cancer, including lung cancer. Recently, the American Society of Clinical Oncology has encouraged preoperative exercise for lung cancer patients. Nonetheless, only limited data, mostly obtained from mouse models of lung cancer, are available on the molecular effects of exercise in lung cancer. Thus, the present minireview aims to shed light on the molecular mechanisms induced by different type of exercise in lung cancer. In particular, the role of the exercise in tumor microenvironment remodeling, angiogenesis, gene expression, apoptosis and intermediate metabolism will be examined.

Indexed as

angiogenesisapoptosisexercisegene expressionintermediate metabolismlung cancertumor microenvironment

Identifiers

PMID39555455
PMCPMC11563951

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.