ArticleIndian journal of surgical oncology2024
Abdominoperineal Resection for T4 Low Rectal Cancer After Neoadjuvant Therapy-Are the Outcomes Acceptable?
Article in Indian journal of surgical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Introduction: There is no clear consensus on using the response MRI as opposed to the pretreatment MRI for surgical planning in cT4 low rectal cancer. The objective of this study is to determine the safety of using response MRI in surgical planning for T4 rectal cancer. Methods: This study is a retrospective review of a prospectively maintained database of abdominoperineal resections conducted at a single tertiary cancer center. Patients undergoing an abdominoperineal resection were divided into 2 groups: group A (clinical T3, mesorectal fascia positive) and group B (clinical T4), and propensity matching was used to account for uneven distribution of baseline characteristics. Primary outcome was the rate of pathological circumferential resection margin positivity. Secondary outcomes were survival outcomes and recurrence patterns. Results: There were 237 patients in group A and 127 in group B, in the unmatched cohort, with a significantly higher number of females (43.3% vs. 28.7%, Conclusion: For T4 low rectal cancers, post-treatment MRI can be used for surgical planning without any detriment in pathological or long-term oncological outcomes. Supplementary Information: The online version contains supplementary material available at 10.1007/s13193-024-02028-3.
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