Evidence map›Paper›PMID 39555016›Full record

ArticleCurrent research in food science2024

Acetate cellulose fibrous scaffold is suitable for cultivated fat production.

Amanda Maria Siqueira Moreira, Júlia Meireles Nogueira, Jade Carceroni, Jorge Luís Guadalupe, Ana Elisa Antunes Dos Santos, Ana Maria Alvarenga Fagundes, Aline Gonçalves Lio Copola, Gerluza Aparecida Borges Silva, Aline Bruna da Silva, João Paulo Ferreira Santos and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current research in food science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Edible Scaffolds for Cultivated Meat Production.Advances in biochemical engineering/biotechnology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Amanda Maria Siqueira MoreiraDepartment of Morphology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Júlia Meireles NogueiraDepartment of Morphology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Jade CarceroniDepartment of Morphology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Jorge Luís GuadalupeDepartment of Morphology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Ana Elisa Antunes Dos SantosDepartment of Morphology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Ana Maria Alvarenga FagundesDepartment of Morphology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Aline Gonçalves Lio CopolaDepartment of Morphology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Gerluza Aparecida Borges SilvaDepartment of Morphology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Aline Bruna da SilvaLaboratory of Biomaterials, Department of Materials Engineering, Federal Center for Technological Education of Minas Gerais (CEFET-MG), Belo Horizonte, Brazil.
João Paulo Ferreira SantosLaboratory of Biomaterials, Department of Materials Engineering, Federal Center for Technological Education of Minas Gerais (CEFET-MG), Belo Horizonte, Brazil.
Juliano Douglas Silva AlbergariaLaboratory of Biomaterials, Department of Materials Engineering, Federal Center for Technological Education of Minas Gerais (CEFET-MG), Belo Horizonte, Brazil.
Luciana de Oliveira AndradeDepartment of Morphology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Erika Cristina JorgeDepartment of Morphology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fat is an essential component of meat which contributes to its sensory characteristics. Therefore, producing cultivated fat is essential to replicate the texture, flavor, and juiciness of conventional meat. One of the challenges in obtaining cultivated fat is that once adipocytes reach differentiation in culture, they tend to float. In this study, we tested whether immortalized pre-adipocytes could be viable, grow, and differentiate when cultivated onto a fibrous scaffold produced by the electrospun of cellulose acetate. Our results demonstrated that the cells attach, proliferate, colonize, and differentiate into mature adipocytes in the three-dimensional fibrous structure during the culture period. Moreover, when layers of the scaffold containing differentiated cells were stacked, it acquired a characteristic similar to conventional animal fat. Therefore, this research suggests that fibrous scaffolds produced using cellulose acetate are a promising substrate for producing cultivated fat.

Indexed as

AdipocytesAdipogenic differentiationCellulose acetateCultivated fatElectrospinningScaffold

Identifiers

PMID39555016
PMCPMC11564054

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.