Evidence map›Paper›PMID 39554977›Full record

ArticleAmerican heart journal plus : cardiology research and practice2024

The evaluation of combined fractional flow reserve and dynamic SPECT in chronic total occlusion.

Shufu Chang, Rende Xu, Hao Lu, Yuxiang Dai, Chenguang Li, Jie Zhang, Gang Zhao, Juying Qian, Jianying Ma, Junbo Ge

Abstract read
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Article in American heart journal plus : cardiology research and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Shufu ChangDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Rende XuDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Hao LuDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Yuxiang DaiDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Chenguang LiDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Jie ZhangDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Gang ZhaoDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Juying QianDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Jianying MaDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Junbo GeDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic total occlusion (CTO) is the most challenging subset in percutaneous coronary intervention (PCI), but the optimal selection of patients and indication for such procedures remain a subject of debate. We sought to investigate the role of physiological function in treatment decisions of CTO PCI by measuring fractional flow reserve (FFR) and Dynamic SPECT imaging in this study. Methods: All the FFR of CTO vessel were measured before and immediately after CTO revascularization, and Dynamic SPECT imaging were detected before PCI in patients with an identified CTO. Results: A total of 53 patients with single-vessel CTO lesions were included in this cohort study. The mean FFR value was 0.34 ± 0.09 at baseline. Immediately after successful CTO PCI, the FFR value significantly increased to 0.79 ± 0.11. The regional coronary flow reserve (CFR) of CTO vessels was 1.62 ± 0.64, which was significantly and positively correlated with the baseline FFR value ( Conclusions: A significant correlation was found between the CFR derived from dynamic SPECT and baseline FFR. An FFR of <0.35 before CTO PCI can be taken as the cutoff for the presence of inducible ischemia, which was a useful index for therapy options.

Indexed as

Chronic total occlusionCoronary flow reserveDynamic SPECTFractional flow reservePercutaneous coronary intervention

Identifiers

PMID39554977
PMCPMC11565035

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