Evidence map›Paper›PMID 39554594›Full record

ArticleFrontiers in signal processing2023

Improved circuitry and post-processing for interleaved fast-scan cyclic voltammetry and electrophysiology measurements.

Ashwin K Avula, Abhinav Goyal, Aaron E Rusheen, Jason Yuen, Warren O Dennis, Diane R Eaker, Joshua B Boesche, Charles D Blaha, Kevin E Bennet, Kendall H Lee and 2 more

Abstract read
In one paragraph

Article in Frontiers in signal processing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ashwin K AvulaDivision of Engineering, Mayo Clinic, Rochester, MN, United States.
Abhinav GoyalDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, United States.
Aaron E RusheenDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, United States.
Jason YuenDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, United States.
Warren O DennisDivision of Engineering, Mayo Clinic, Rochester, MN, United States.
Diane R EakerDivision of Engineering, Mayo Clinic, Rochester, MN, United States.
Joshua B BoescheDivision of Engineering, Mayo Clinic, Rochester, MN, United States.
Charles D BlahaDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, United States.
Kevin E BennetDivision of Engineering, Mayo Clinic, Rochester, MN, United States.
Kendall H LeeDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, United States.
Hojin ShinDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, United States.
Yoonbae OhDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, United States.

Funding

TRAINING IN TRANSLATIONAL RESEARCH: BENCH TO BEDSIDER25GM055252 · NIGMS · MAYO CLINIC ROCHESTER · PI LUJAN, LUIS, MAHER, LOUIS JAMES · 1996 to 2022
$8.3M
NRSA Training CoreTL1TR002380 · NCATS · MAYO CLINIC ROCHESTER · PI Felicity T. B. Enders, ANTHONY John WINDEBANK · 2017 to 2026
$6.0M
Medical Scientist Traning Program at Mayo ClinicT32GM065841 · NIGMS · MAYO CLINIC ROCHESTER · PI KAUFMANN, SCOTT H, SCHIMMENTI, LISA A · 2003 to 2022
$5.8M
An Integrated Neurochemical/Electrophysiological Recording and Neuromodulation System for Basic and Clinical ResearchR42NS125895 · NINDS · WINCS INTERNATIONAL, LLC · PI Kevin Elliott Bennet, Kendall Lee · 2022 to 2026
$2.3M
Development of an innovative in vivo voltammetric technique for measurements of tonic serotonin concentrations in the mammalian brain.R01NS129549 · NINDS · MAYO CLINIC ROCHESTER · PI Kendall H. Lee, Yoonbae Oh · 2023 to 2026
$2.3M
Development of advanced voltammetric method for basal neurotransmitter level measurementR01NS112176 · NINDS · MAYO CLINIC ROCHESTER · PI LEE, KENDALL H., OH, YOONBAE · 2019 to 2022
$1.4M
Mechanism of CMPf Deep Brain Stimulation for Tourette SyndromeF31NS115202 · NINDS · MAYO CLINIC ROCHESTER · PI RUSHEEN, AARON ELLIOTT · 2020 to 2023
$195k
Elucidating the neurochemical basis of LTP induction and maintenance in vivoF30MH131254 · NIMH · MAYO CLINIC ROCHESTER · PI GOYAL, ABHINAV · 2022 to 2025
$172k
NCATS NIH HHS TL1 TR002380NIGMS NIH HHS R25 GM055252NIGMS NIH HHS T32 GM065841NIMH NIH HHS F30 MH131254NINDS NIH HHS F31 NS115202NINDS NIH HHS R01 NS112176NINDS NIH HHS R01 NS129549NINDS NIH HHS R42 NS125895
6 · The paper itself

Abstract

The combination of electrophysiology and electrochemistry acquisition methods using a single carbon fiber microelectrode (CFM) in the brain has enabled more extensive analysis of neurochemical release, neural activity, and animal behavior. Predominantly, analog CMOS (Complementary Metal Oxide Semiconductor) switches are used for these interleaved applications to alternate the CFM output between electrophysiology and electrochemistry acquisition circuitry. However, one underlying issue with analog CMOS switches is the introduction of transient voltage artifacts in recorded electrophysiology signals resulting from CMOS charge injection. These injected artifacts attenuate electrophysiology data and delay reliable signal observation after every switch actuation from electrochemistry acquisition. Previously published attempts at interleaved electrophysiology and electrochemistry were able to recover reliable electrophysiology data within approximately 10-50 ms after switch actuation by employing various high-pass filtering methods to mitigate the observed voltage artifacts. However, high-pass filtering of this nature also attenuates valuable portions of the local-field potential (LFP) frequency range, thus limiting the extent of network-level insights that can be derived from

Indexed as

dopamineelectrochemistryelectrophysiological recordingfast-scan cyclic voltammetrypost signal processing

Identifiers

PMID39554594
PMCPMC11567673

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.