Evidence map›Paper›PMID 39554548›Full record

ArticleData in brief2024

Proteomics dataset of lysolecithin-induced demyelinated lesions in corpus callosum of Lewis rats, treated with Vagus nerve stimulation or sham treatment.

Helen Bachmann, Boris Vandemoortele, Vanessa Vermeirssen, Evelien Carrette, Kristl Vonck, Paul Boon, Robrecht Raedt, Guy Laureys

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Data in brief, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Helen Bachmann4Brain, Department of Neurology, Ghent University, Ghent University Hospital, Corneel Heymanslaan 10, 9000 Ghent, Belgium.
Boris VandemoorteleLaboratory for Computational Biology, Integromics and Gene Regulation (CBIGR), Cancer Research Institute Ghent (CRIG), Corneel Heymanslaan 10, 9000 Ghent, Belgium.
Vanessa VermeirssenLaboratory for Computational Biology, Integromics and Gene Regulation (CBIGR), Cancer Research Institute Ghent (CRIG), Corneel Heymanslaan 10, 9000 Ghent, Belgium.
Evelien Carrette4Brain, Department of Neurology, Ghent University, Ghent University Hospital, Corneel Heymanslaan 10, 9000 Ghent, Belgium.
Kristl Vonck4Brain, Department of Neurology, Ghent University, Ghent University Hospital, Corneel Heymanslaan 10, 9000 Ghent, Belgium.
Paul Boon4Brain, Department of Neurology, Ghent University, Ghent University Hospital, Corneel Heymanslaan 10, 9000 Ghent, Belgium.
Robrecht Raedt4Brain, Department of Neurology, Ghent University, Ghent University Hospital, Corneel Heymanslaan 10, 9000 Ghent, Belgium.
Guy Laureys4Brain, Department of Neurology, Ghent University, Ghent University Hospital, Corneel Heymanslaan 10, 9000 Ghent, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article presents a comprehensive proteomics dataset from a lysolecithin (LPC)-induced demyelination model in the corpus callosum of female Lewis rats. The LPC model, widely used in preclinical studies of toxic demyelination, serves as a valuable tool for investigating processes of demyelination and remyelination, as well as for testing potential remyelination therapies for diseases like Multiple Sclerosis. In this study, rats received either Vagus Nerve Stimulation (VNS) or a sham treatment. Proteomic analysis via LC-MS/MS was performed to assess the impact of these treatments on inflammation and remyelination and to further explore the mechanism of VNS action. This dataset complements the findings reported in the article "

Indexed as

Corpus callosumDemyelinationLysolecithinProteomicsRatVagus Nerve Stimulation

Identifiers

PMID39554548
PMCPMC11567096

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.