Evidence map›Paper›PMID 39554503›Full record

ArticleFrontiers in medicine2024

Uremic sarcopenia: the role of intramuscular adipose tissue as a potential early identifier.

Annalisa Noce, Maria Josè Ceravolo, Paola Gualtieri, Giulia Marrone, Lorenzo Romano, Amir Shoshi, Manuela Di Lauro, Antonino De Lorenzo

Abstract read
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In one paragraph

Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Annalisa NoceDepartment of Systems Medicine, University of Rome Tor Vergata, Rome, RM, Italy.
Maria Josè CeravoloUOSD Nephrology and Dialysis, Policlinico Tor Vergata, Rome, RM, Italy.
Paola GualtieriSection of Clinical Nutrition and Nutrigenomics, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, RM, Italy.
Giulia MarroneDepartment of Systems Medicine, University of Rome Tor Vergata, Rome, RM, Italy.
Lorenzo RomanoSection of Clinical Nutrition and Nutrigenomics, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, RM, Italy.
Amir ShoshiProgram in Specialization in Nephrology, Catholic University Our Lady of Good Counsel, Tirana, Albania.
Manuela Di LauroDepartment of Systems Medicine, University of Rome Tor Vergata, Rome, RM, Italy.
Antonino De LorenzoSection of Clinical Nutrition and Nutrigenomics, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, RM, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Sarcopenia is a chronic pathological condition, first defined in 2010 and revised in 2018. The most recent definition of sarcopenia focuses mostly on "low muscle strength." A secondary form of sarcopenia is represented by uremic sarcopenia (US), a condition that characterizes end-stage kidney disease (ESKD) patients. The intramuscular adipose tissue (IMAT) seems to impact negatively on muscle strength, as it would seem to replace muscle fibers with a non-contractile component. The study aims to compare body composition parameters-both standardized and innovative-related to the diagnosis of US in hemodialysis (HD) patients, stratified by sarcopenia diagnosis. Furthermore, the different indices of sarcopenia are compared in order to evaluate their predictive capacity. Methods: We analyzed 48 ESKD patients according to the sarcopenia diagnosis, obtained using dual-energy X-ray absorptiometry (DXA). Moreover, we assessed the presence of IMAT and calculated the sarcopenia index (SI). Results: For the study, the enrolled population was divided according to the sarcopenia diagnosis: no sarcopenic patients had higher transferrin (

Indexed as

body composition analysisdialysis patientsintramuscular adipose tissueparathyroid hormonesarcopenia indexuremic sarcopenia

Identifiers

PMID39554503
PMCPMC11563970

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.