Evidence map›Paper›PMID 39554349›Full record

ReviewFood science & nutrition2024

Structure and regulatory mechanisms of food-derived peptides in inflammatory bowel disease: A review.

Wenpei Qiu, Zhicheng Wang, Qirui Liu, Qiwei Du, Xiaoqun Zeng, Zhen Wu, Daodong Pan, Xiaohong Zhang, Maolin Tu

Abstract readReview
In one paragraph

Review in Food science & nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Marine Collagen Peptide Fraction fromFoods (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wenpei QiuState Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products Ningbo University Ningbo Zhejiang China.
Zhicheng WangState Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products Ningbo University Ningbo Zhejiang China.
Qirui LiuZhejiang-Malaysia Joint Research Laboratory for Agricultural Product Processing and Nutrition, College of Food Science and Engineering Ningbo University Ningbo China.
Qiwei DuState Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products Ningbo University Ningbo Zhejiang China.
Xiaoqun ZengState Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products Ningbo University Ningbo Zhejiang China.
Zhen WuState Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products Ningbo University Ningbo Zhejiang China.
Daodong PanState Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products Ningbo University Ningbo Zhejiang China.
Xiaohong ZhangSchool of Medicine Ningbo University Ningbo China.
Maolin TuState Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products Ningbo University Ningbo Zhejiang China.ORCID https://orcid.org/0000-0003-3417-9443

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The number of patients with inflammatory bowel disease (IBD) is increasing worldwide. Since IBD is a chronic disease that seriously affects patients' life quality, preventing and alleviating IBD with natural and less side effect substances has become a research hotspot. Food-derived bioactive peptides have been an attractive research focus due to their high efficiency and low toxicity. This paper comprehensively summarizes food-derived peptides with intestinal health effects, focusing on peptide sequences with IBD-regulatory effects and emphasizing the effects of their structure and physicochemical properties such as peptide length, amino acid composition, and net charge on their function. We also analyzed its regulatory mechanisms, mainly in 5 aspects: modulating the intestinal microbiota, decreasing intestinal epithelial permeability, increasing antioxidant ability, regulating the expression of inflammatory cytokines, and targeting signaling pathways. This review will help establish novel, efficient screening methods for IBD-regulatory peptides and contribute to further research and discovery of them.

Indexed as

food‐derived bioactive peptideinflammatory bowel diseasepeptide structureregulatory mechanism

Identifiers

PMID39554349
PMCPMC11561845

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.