Evidence map›Paper›PMID 39554221›Full record

ArticleChina CDC weekly2024

AI-Based Hematological Age Predictors and the Association Between Biological Age Acceleration and Type 2 Diabetes Mellitus - Chongqing Municipality, China, 2015-2021.

Zhe Yin, Yingnan Song, Junhui Zhang, Qiaoyun Dai, Xinyuan Zhang, Xueying Yang, Na Nie, Cuixia Chen, Zongfu Cao, Xu Ma

Abstract read
In one paragraph

Article in China CDC weekly, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. AI-Driven Management of Type 2 Diabetes in China: Opportunities and Challenges.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhe YinNational Human Genetic Resources Center, National Research Institute for Family Planning, Beijing, China.
Yingnan SongChinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Junhui ZhangThe First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Qiaoyun DaiNational Human Genetic Resources Center, National Research Institute for Family Planning, Beijing, China.
Xinyuan ZhangNational Human Genetic Resources Center, National Research Institute for Family Planning, Beijing, China.
Xueying YangNational Human Genetic Resources Center, National Research Institute for Family Planning, Beijing, China.
Na NieThe First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Cuixia ChenNational Human Genetic Resources Center, National Research Institute for Family Planning, Beijing, China.
Zongfu CaoNational Human Genetic Resources Center, National Research Institute for Family Planning, Beijing, China.
Xu MaNational Human Genetic Resources Sharing Service Platform, National Research Institute for Family Planning, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Biological age (BA) can represent the actual state of human aging more accurately than chronological age (CA). Methods: Using hematological data from 112,925 participants in southwestern China, collected between 2015 and 2021, this study constructed BA predictors using 7 machine learning (ML) methods (tailored separately for male and female populations). This study then analyzed the association between BA acceleration and type 2 diabetes mellitus (T2DM) within this data using logistic regression. Additionally, it examined the impact of glycemic control on BA in individuals with diabetes. Results: Among all ML models, deep neural networks (DNN) delivered the best performance in male [mean absolute error (MAE)=6.89, r=0.75] and female subsets (MAE=6.86, r=0.74). BA acceleration showed positive correlations with T2DM in both male [odds ratio ( Discussion: Artificial intelligence (AI)-based hematological BA predictors show promise as advanced tools for assessing aging in epidemiological studies. Implementing AI-based BA predictors in public health initiatives could facilitate proactive aging management and disease prevention.

Indexed as

Hematological biological ageMachine learningType 2 diabetes mellitus

Identifiers

PMID39554221
PMCPMC11561367

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.