Evidence map›Paper›PMID 39554183›Full record

ArticlebioRxiv : the preprint server for biology2024

Microbial transcriptional responses to host diet maintain gut microbiome homeostasis in the American cockroach.

Amber N DePoy, Helen E Wall, Kara A Tinker, Elizabeth A Ottesen

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amber N DePoyDepartment of Microbiology, University of Georgia, Athens, Georgia, USA.ORCID 0000-0002-0697-4733
Helen E WallDepartment of Microbiology, University of Georgia, Athens, Georgia, USA.ORCID 0000-0002-2229-5773
Kara A TinkerDepartment of Microbiology, University of Georgia, Athens, Georgia, USA.ORCID 0000-0002-4860-6277
Elizabeth A OttesenDepartment of Microbiology, University of Georgia, Athens, Georgia, USA.ORCID 0000-0002-7898-2425

Funding

Dissecting host and microbial contributions to gut microbiome homeostasisR35GM133789 · NIGMS · UNIVERSITY OF GEORGIA · PI OTTESEN, ELIZABETH A · 2019 to 2023
$1.9M
NIGMS NIH HHS R35 GM133789
6 · The paper itself

Abstract

Diet is considered a key determinant of gut microbiome composition and function. However, studies in the American cockroach have revealed surprising stability in hindgut microbiome taxonomic composition following shifts in host diet. To discover microbial activities underlying this stability, we analyzed microbial community transcriptomes from hindguts of cockroaches fed diverse diets. We used a taxon-centric approach in which we clustered genomes based on taxonomic relatedness and functional similarity and examined the transcriptional profiles of each cluster independently. In total, we analyzed a set of 18 such "genome clusters", including key taxa within

Identifiers

PMID39554183
PMCPMC11565919

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.