Evidence map›Paper›PMID 39554152›Full record

ArticlebioRxiv : the preprint server for biology2025

Effects of intergenerational transmission of small intestinal bacteria cultured from stunted Bangladeshi children with enteropathy.

Kali M Pruss, Clara Kao, Alexandra E Byrne, Robert Y Chen, Blanda Di Luccia, Laura Karvelyte, Reyan Coskun, Mackenzie Lemieux, Keshav Nepal, Daniel M Webber and 11 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Kali M PrussThe Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine; St. Louis, MO 63110, USA.ORCID 0000-0002-8619-5886
Clara KaoThe Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine; St. Louis, MO 63110, USA.
Alexandra E ByrneThe Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine; St. Louis, MO 63110, USA.
Robert Y ChenThe Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine; St. Louis, MO 63110, USA.
Blanda Di LucciaThe Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine; St. Louis, MO 63110, USA.
Laura KarvelyteDivision of Immunobiology, Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO 63110, USA.
Reyan CoskunThe Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine; St. Louis, MO 63110, USA.
Mackenzie LemieuxThe Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine; St. Louis, MO 63110, USA.
Keshav NepalThe Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine; St. Louis, MO 63110, USA.
Daniel M WebberThe Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine; St. Louis, MO 63110, USA.
Matthew C HibberdThe Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine; St. Louis, MO 63110, USA.
Yi WangThe Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine; St. Louis, MO 63110, USA.
Haoxin LiuThe Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine; St. Louis, MO 63110, USA.
Dmitry A RodionovInfectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037 USA.
Andrei L OstermanInfectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037 USA.ORCID 0000-0002-3810-9824
Marco ColonnaDivision of Immunobiology, Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO 63110, USA.ORCID 0000-0001-5222-4987
Christian MaueroderInflammation Research Centre, VIB, and the Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
Kodi RavichandranDivision of Immunobiology, Department of Pathology and Immunology, Washington University School of Medicine; St. Louis, MO 63110, USA.
Michael J BarrattThe Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine; St. Louis, MO 63110, USA.
Tahmeed AhmedInternational Center for Diarrhoeal Disease Research, Bangladesh (icddr,b); Dhaka 1212, Bangladesh.
Jeffrey I GordonThe Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine; St. Louis, MO 63110, USA.

Funding

The small intestinal microbiota in undernourished women and undernourished children in Bangladesh: identifying causal mechanisms and therapeutic targetsR01DK131107 · NIDDK · WASHINGTON UNIVERSITY · PI GORDON, JEFFREY I · 2021 to 2024
$4.1M
Solute carrier proteins in efferocytosis and inflammationR01AI159551 · NIAID · WASHINGTON UNIVERSITY · PI RAVICHANDRAN, KODI S · 2021 to 2025
$2.9M
Solute carrier proteins and metal ion-based signaling during efferocytosisR37AI159551 · NIAID · WASHINGTON UNIVERSITY · PI Kodi S Ravichandran · 2026 to 2026
$611k
Impact of Gut Bacterial Interactions on the Response to Fiber-Based PrebioticsF30DK123838 · NIDDK · WASHINGTON UNIVERSITY · PI BELLER, ZACHARY WALTER · 2020 to 2022
$127k
Bill & Melinda Gates Foundation INV-033564NIAID NIH HHS R01 AI159551NIAID NIH HHS R37 AI159551NIDDK NIH HHS F30 DK123838NIDDK NIH HHS R01 DK131107
6 · The paper itself

Abstract

Environmental enteric dysfunction (EED), a small intestinal disorder found at a high prevalence in stunted children, is associated with gut mucosal barrier disruption and decreased absorptive capacity

Identifiers

PMID39554152
PMCPMC11566026

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.