Evidence map›Paper›PMID 39554100›Full record

ArticlebioRxiv : the preprint server for biology2025

Reactive Oxygen Detoxification Contributes to

Nicholas A Bates, Ronald Rodriguez, Rama Drwich, Abigail Ray, Sarah A Stanley, Bennett H Penn

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Nicholas A BatesDepartment of Internal Medicine, University of California, Davis, California, USA.
Ronald RodriguezDepartment of Molecular & Cell Biology, University of California, Berkeley, California, USA.
Rama DrwichDepartment of Internal Medicine, University of California, Davis, California, USA.
Abigail RayMicrobiology Graduate Group, University of California, Davis, California, USA.
Sarah A StanleyDepartment of Molecular & Cell Biology, University of California, Berkeley, California, USA.
Bennett H PennDepartment of Internal Medicine, University of California, Davis, California, USA.

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI KC KENT LLOYD · 2002 to 2026
$84.9M
Understanding How the Ubiquitin Ligase CBL Regulates Innate Immune ResponsesR01AI144149 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI PENN, BENNETT · 2019 to 2023
$2.4M
The role of nanocompartments in M. tuberculosis pathogenesisR01AI143722 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI STANLEY, SARAH A · 2019 to 2023
$1.9M
Acquisition of Covaris E220 and Sciclone G3 systems for high throughput sequencinS10OD010786 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI COMAI, LUCA · 2012 to 2012
$311k
NCI NIH HHS P30 CA093373NIAID NIH HHS R01 AI143722NIAID NIH HHS R01 AI144149NIH HHS S10 OD010786
6 · The paper itself

Abstract

When a population of bacteria are exposed to a bactericidal antibiotic most cells die rapidly. However, a sub-population of antibiotic-tolerant cells known as "persister cells" can survive for prolonged periods, and antibiotic tolerance can be strongly induced in a population by stresses such as nutrient deprivation. However, the pathways required to maintain viability in this setting, and how they are regulated are poorly understood. To identify genetic determinants of antibiotic tolerance in mycobacteria, we carried out transposon mutagenesis insertion sequencing (Tn-Seq) screens in

Identifiers

PMID39554100
PMCPMC11565942

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.