Evidence map›Paper›PMID 39554071›Full record

ArticlebioRxiv : the preprint server for biology2024

Altered AP-1, RUNX and EGR chromatin dynamics drive fibrotic lung disease.

Eleanor Valenzi, Minxue Jia, Peter Gerges, Jingyu Fan, Tracy Tabib, Rithika Behara, Yuechen Zhou, John Sembrat, Jishnu Das, Panayiotis V Benos and 2 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Eleanor ValenziDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh.
Minxue JiaDepartment of Computational and Systems Biology, University of Pittsburgh.
Peter GergesCenter for Systems Immunology and Department of Immunology, University of Pittsburgh.
Jingyu FanCenter for Systems Immunology and Department of Immunology, University of Pittsburgh.
Tracy TabibDivision of Rheumatology and Clinical Immunology, University of Pittsburgh.
Rithika BeharaDivision of Rheumatology and Clinical Immunology, University of Pittsburgh.
Yuechen ZhouDivision of Rheumatology and Clinical Immunology, University of Pittsburgh.
John SembratDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh.
Jishnu DasCenter for Systems Immunology and Department of Immunology, University of Pittsburgh.ORCID 0000-0002-5747-064X
Panayiotis V BenosDepartment of Computational and Systems Biology, University of Pittsburgh.ORCID 0000-0003-3172-3132
Harinder SinghCenter for Systems Immunology and Department of Immunology, University of Pittsburgh.
Robert LafyatisDivision of Rheumatology and Clinical Immunology, University of Pittsburgh.

Funding

Systems Biology CoreP50AR080612 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Robyn Therese Domsic · 2022 to 2026
$9.5M
Uncovering the genomic regulatory network of myofibroblast differentiation in systemic sclerosis-associated interstitial lung diseaseK08HL161258 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Eleanor Valenzi · 2022 to 2026
$806k
High-Throughput Computing for Genomics and Bioinformatics ResearchS10OD028483 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LEE, ADRIAN V · 2021 to 2021
$574k
NHLBI NIH HHS K08 HL161258NIAMS NIH HHS P50 AR080612NIH HHS S10 OD028483
6 · The paper itself

Abstract

Pulmonary fibrosis, including systemic sclerosis-associated interstitial lung disease (SSc-ILD), involves myofibroblasts and SPP1

Identifiers

PMID39554071
PMCPMC11565795

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.