ArticleBiomicrofluidics2024
Viscoelastic particle focusing and separation in a microfluidic channel with a cruciform section.
Article in Biomicrofluidics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Considerable attention has been given to elasto-inertial microfluidics, which are widely applied for the focusing, sorting, and separation of particles/cells. In this work, we propose a novel yet simple fabrication process for a microchannel with a cruciform section, where elasto-inertial particle focusing is explored in a viscoelastic fluid. SU-8 master molds for polydimethylsiloxane (PDMS) structures were fabricated via standard photolithography, and then plasma bonding, following self-alignment between two PDMS structures, was performed for the formation of a microchannel with a cruciform section. The particle behaviors inside the fabricated microchannel were experimentally investigated for various flow rates and particle sizes and compared with those inside a microchannel with a square cross section. The experimental results revealed that 3D particle focusing was achieved in the center under viscoelastic fluid flow over a wide range of flow rates without any shear thinning. Even for small particles (∼2
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