Evidence map›Paper›PMID 39553909›Full record

ArticleJACC. Asia2024

A Novel Model of Integrated Care of Older Patients With Atrial Fibrillation in Rural China.

Mingfang Li, Ming Chu, Youmei Shen, Shimeng Zhang, Xuejun Yin, Shu Yang, Gregory Y H Lip, Minglong Chen, MIRACLE-AF Trial Investigators

3 registry-linked trialsAbstract read
In one paragraph

Article in JACC. Asia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04622514 nacompletednot on this map

A New Model of Integrated Care of Older Patients With Atrial Fibrillation in Rural China: a Cluster Randomization Trial (the MIRACLE-AF Trial)

TypeinterventionalSponsorThe First Affiliated Hospital with Nanjing Medical UniversityRan2020 to 2024Enrolled1,039ConditionsAtrial Fibrillation, Older, StrokeArmsVillage doctor-led telemedicine integrated care, Enhanced usual care
NCT07492498 narecruitingnot on this mapstarted 2026, after this paper: background citation

Novel Model of Integrated Care of Older Patients With Atrial Fibrillation to Prevent Heart Failure in Rural China

TypeinterventionalSponsorJiangsu Taizhou People's HospitalRan2026 to 2030Enrolled1,356ConditionsAtrial Fibrillation, Heart FailureArmsVillage-Doctor Led Integrated Care, Usual Care
NCT07492524 narecruitingnot on this mapstarted 2026, after this paper: background citation

Novel Model of Integrated Care of Older Patients With Atrial Fibrillation and Heart Failure in Rural China (MIRACLE-AFHF)

TypeinterventionalSponsorJiangsu Taizhou People's HospitalRan2026 to 2029Enrolled942ConditionsAtrial Fibrillation, Heart FailureArmsVillage-Doctor Led Integrated Care, Usual Care
3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Cognitive function and telemedicine-based, village doctor-led care for atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
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  5. From Integrated Care to Learning Systems.Healthcare (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mingfang LiDivision of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Ming ChuDivision of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Youmei ShenDivision of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Shimeng ZhangDivision of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xuejun YinSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Shu YangDivision of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Gregory Y H LipLiverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool John Moores University and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom; and the Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Minglong ChenDivision of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
MIRACLE-AF Trial Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: An integrated management approach is essential to improving outcomes for patients with atrial fibrillation (AF). China's rural health care system, primarily reliant on village doctors, falls short of providing optimal management of AF in rural populations with limited resources and access to health care. To support village doctors in providing integrated care for AF, we have developed a digital health support platform. Objectives: This study aims to evaluate the effectiveness of this telemedicine-based, village doctor-led, multifaceted care model. Methods: The MIRACLE-AF (a novel Model of IntegRAted Care of oLdEr patients with Atrial Fibrillation in rural China) trial is a prospective cluster-randomized clinical trial. Thirty village clinics in Jiangdu County, Jiangsu Province, were randomly assigned to village doctor-led telemedicine integrated care or enhanced usual care in a 1:1 ratio. All the patients diagnosed with AF who resided in this rural area and were aged ≥65 years were eligible for enrollment. The primary outcome in stage 1 was the proportion of patients who met all 3 criteria for the atrial fibrillation better care pathway at 12 months, and in stage 2, a composite of cardiovascular death, all strokes including ischemic stroke and hemorrhagic stroke, worsening of heart failure or acute coronary syndrome, and emergency visits due to AF over 36 months. Results: In total, 1,039 participants were recruited from December 1, 2020, to May 9, 2022, with 524 in the telemedicine care arm and 515 in the enhanced usual care arm. All the enrolled patients are under scheduled follow-up. Conclusions: The MIRACLE-AF trial will provide evidence for this novel integrated care model for treating rural older patients with AF. (New Model of Integrated Care of Older Patients with Atrial Fibrillation in Rural China; NCT04622514).

Indexed as

atrial fibrillationintegrated managementolder patientsrural areatelemedicine

Identifiers

PMID39553909
PMCPMC11561497

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.