Evidence map›Paper›PMID 39553826›Full record

ArticleJAMIA open2024

Addressing ethical issues in healthcare artificial intelligence using a lifecycle-informed process.

Benjamin X Collins, Jean-Christophe Bélisle-Pipon, Barbara J Evans, Kadija Ferryman, Xiaoqian Jiang, Camille Nebeker, Laurie Novak, Kirk Roberts, Martin Were, Zhijun Yin and 7 more

Abstract read
In one paragraph

Article in JAMIA open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Benjamin X CollinsDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37203, United States.ORCID https://orcid.org/0000-0002-6884-3819
Jean-Christophe Bélisle-PiponFaculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada.
Barbara J EvansLe vin College of Law, University of Florida, Gainesville, FL 32611, United States.ORCID https://orcid.org/0000-0001-8115-7971
Kadija FerrymanBerman Institute of Bioethics, Johns Hopkins University, Baltimore, MD 21205, United States.
Xiaoqian JiangMcWilliams School of Biomedical Informatics, UTHealth Houston, Houston, TX 77030, United States.ORCID https://orcid.org/0000-0001-9933-2205
Camille NebekerHerbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla, CA 92093, United States.
Laurie NovakDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37203, United States.
Kirk RobertsMcWilliams School of Biomedical Informatics, UTHealth Houston, Houston, TX 77030, United States.
Martin WereDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37203, United States.ORCID https://orcid.org/0000-0002-6182-093X
Zhijun YinDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37203, United States.
Vardit RavitskyThe Hastings Center, Garrison, NY 10524, United States.ORCID https://orcid.org/0000-0002-7080-8801
Joseph CocoDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37203, United States.
Rachele Hendricks-SturrupNational Alliance against Disparities in Patient Health, Woodbridge, VA 22191, United States.
Ishan WilliamsSchool of Nursing, University of Virginia, Charlottesville, VA 22903, United States.
Ellen W ClaytonCenter for Biomedical Ethics and Society, Vanderbilt University Medical Center, Nashville, TN 37203, United States.
Bradley A MalinDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37203, United States.
Bridge2AI Ethics and Trustworthy AI Working Group

Funding

Bridge2AI:Salutogenesis Data Generation ProjectOT2OD032644 · OD · WASHINGTON UNIVERSITY · PI BAXTER, SALLY LIU, CHUTE, CHRISTOPHER G · 2022 to 2025
$32.7M
Bridge2AI: Patient-Focused Collaborative Hospital Repository Uniting Standards (CHoRUS) for Equitable AIOT2OD032701 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI BIHORAC, AZRA, CLERMONT, GILLES · 2022 to 2025
$24.6M
Bridge2AI: Cell Maps for AI (CM4AI) Data Generation ProjectOT2OD032742 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jean-Christophe Bélisle-Pipon, TIMOTHY W CLARK · 2022 to 2026
$21.5M
Bridge2AI: Voice as a Biomarker of Health - Building an ethically sourced, bioaccoustic database to understand disease like never beforeOT2OD032720 · OD · UNIVERSITY OF SOUTH FLORIDA · PI BENSOUSSAN, YAEL EMILIE, BÉLISLE-PIPON, JEAN-CHRISTOPHE · 2022 to 2025
$18.0M
Ethics Core (FABRIC)U54HG012510 · NHGRI · YALE UNIVERSITY · PI MALIN, BRADLEY A. · 2022 to 2025
$11.2M
Tool Core- BoutrosU54HG012517 · NHGRI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WATSON, KAROL E · 2022 to 2025
$10.6M
Integration, Dissemination and Evaluation(BRIDGE) Center for the NIH Bridge to Artificial Intelligence (BRIDGE2AI) ProgramU54HG012513 · NHGRI · UNIVERSITY OF COLORADO DENVER · PI MUNOZ-TORRES, MONICA CECILIA · 2022 to 2025
$9.5M
NHGRI NIH HHS U54 HG012510NHGRI NIH HHS U54 HG012513NHGRI NIH HHS U54 HG012517NIH HHS OT2 OD032644NIH HHS OT2 OD032701NIH HHS OT2 OD032720NIH HHS OT2 OD032742
6 · The paper itself

Abstract

Objectives: Artificial intelligence (AI) proceeds through an iterative and evaluative process of development, use, and refinement which may be characterized as a lifecycle. Within this context, stakeholders can vary in their interests and perceptions of the ethical issues associated with this rapidly evolving technology in ways that can fail to identify and avert adverse outcomes. Identifying issues throughout the AI lifecycle in a systematic manner can facilitate better-informed ethical deliberation. Materials and Methods: We analyzed existing lifecycles from within the current literature for ethical issues of AI in healthcare to identify themes, which we relied upon to create a lifecycle that consolidates these themes into a more comprehensive lifecycle. We then considered the potential benefits and harms of AI through this lifecycle to identify ethical questions that can arise at each step and to identify where conflicts and errors could arise in ethical analysis. We illustrated the approach in 3 case studies that highlight how different ethical dilemmas arise at different points in the lifecycle. Results Discussion and Conclusion: Through case studies, we show how a systematic lifecycle-informed approach to the ethical analysis of AI enables mapping of the effects of AI onto different steps to guide deliberations on benefits and harms. The lifecycle-informed approach has broad applicability to different stakeholders and can facilitate communication on ethical issues for patients, healthcare professionals, research participants, and other stakeholders.

Indexed as

artificial intelligenceethicshealthcare

Identifiers

PMID39553826
PMCPMC11565898

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.