Evidence map›Paper›PMID 39553758›Full record

ArticleOpen veterinary journal2024

Factors associated with success rate of oral force-feeding ammonium chloride administration to acidify urine in goats.

Phitcha Pongphitcha, Kanyarat Chuchoed, Thitiporn Thetsana, Napassorn Dachphun, Patskit Sukhong, Niorn Ratanapob

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Article in Open veterinary journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Phitcha PongphitchaKasetsart University Veterinary Teaching Hospital Kamphaeng Saen, Kasetsart University, Nakhon Pathom, Thailand.
Kanyarat ChuchoedDVM Students, Faculty of Veterinary Medicine, Kasetsart University, Bangkok, Thailand.
Thitiporn ThetsanaDVM Students, Faculty of Veterinary Medicine, Kasetsart University, Bangkok, Thailand.
Napassorn DachphunDVM Students, Faculty of Veterinary Medicine, Kasetsart University, Bangkok, Thailand.
Patskit SukhongDeperment of Large Animal and Wildlife Clinical Sciences, Faculty of Veterinary Medicine, Kasetsart University, Nakhon Pathom, Thailand.
Niorn RatanapobDeperment of Large Animal and Wildlife Clinical Sciences, Faculty of Veterinary Medicine, Kasetsart University, Nakhon Pathom, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ammonium chloride is the most common urine acidifier used for urolithiasis treatment and prevention in goats. Aim: The objective of this study was to determine a guideline for ammonium chloride administration to acidify urine in goats. Methods: A three-period, three-treatment crossover study was conducted in three groups, with 10 female goats in each group. Three dosages of ammonium chloride were used (250, 350, or 450 mg/kg). In each experimental period, ammonium chloride was orally administered for three consecutive days or until the urine pH dropped below 6.5. Urine samples were collected to measure the pH before each administration and 1 day after the last administration. The Cox proportional hazards model was conducted to identify factors associated with the success rate in reducing the urine pH below 6.5 at a time. Results: The dosage of ammonium chloride and period of administration were significantly associated with the success rate ( Conclusion: The recommended ammonium chloride dosage was 350 mg/kg. Periodic use can be considered to achieve better outcomes. The pretreatment urine pH should be measured to anticipate the clinical response.

Indexed as

Ammonium ChlorideCross-Over StudiesGoatsAdministration, OralAnimalsFemaleGoat DiseasesHydrogen-Ion ConcentrationUrineUrolithiasisAmmonium ChlorideAmmonium chlorideGoatSuccess rateUrine acidificationUrolithiasis

Identifiers

PMID39553758
PMCPMC11563597

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.