Evidence map›Paper›PMID 39553563›Full record

ArticleHeliyon2024

Risk factors for recurrence of Mooren's ulcer after keratoplasty.

Shangkun Ou, Yujie Zhang, Yuan Lin, Xie Fang, Zhiwen Xie, Ke Shi, Minqing Cai, Shengqi Su, Huping Wu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shangkun OuXiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, Xiamen, China.
Yujie ZhangXiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, Xiamen, China.
Yuan LinXiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, Xiamen, China.
Xie FangXiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, Xiamen, China.
Zhiwen XieXiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, Xiamen, China.
Ke ShiXiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, Xiamen, China.
Minqing CaiXiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, Xiamen, China.
Shengqi SuXiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, Xiamen, China.
Huping WuXiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, Xiamen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The purpose of this study was to investigate the clinical characteristics of patients with corneal Mooren's ulcers (MU) and explore potential risk factors for recurrence after keratoplasty. Methods: The study retrospectively analyzed 87 patients (101 eyes) diagnosed with MU. Factors associated with recurrence after keratoplasty were identified using correlation analysis, and a clinical scoring system was developed based on the magnitude of the univariate and multivariate logistic regression analysis. Results: The average age of onset for the 87 patients was 55.2 years old, and the male-to-female ratio was 1:0.74. Of the 101 eyes diagnosed with MU, 73 cases (83.9 %) were Unilateral. Eleven eyes (10.9 %) had a history of ocular surgery, and five (5.0 %) had a history of ocular trauma. The perforation rate was 18.8 %, and the recurrence rate after keratoplasty was 37.3 %. Ulcer depth (P < 0.05, R = -0.252), corneal perforation status (P < 0.05, R = 0.238), and history of ocular surgery or trauma (P < 0.05, R = -0.238) were associated with recurrence. Based on these findings, a clinical scoring system was constructed to evaluate the recurrence of MU. Conclusion: MU mostly occurs in elderly men, often with monocular onset. The recurrence rate after keratoplasty is high at 37.3 %. Deep ulcer infiltration, corneal perforation, and a history of ocular surgery or trauma are associated with recurrence after keratoplasty. A scoring system has been established based on these clinical characteristics and can be used to predict the risk of recurrence after keratoplasty.

Indexed as

Clinical characteristicsClinical scoring systemCorneal perforationMooren's ulcerRecurrenceTreatment

Identifiers

PMID39553563
PMCPMC11567018

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