Evidence map›Paper›PMID 39553434›Full record

ReviewBioengineering & translational medicine2024

Eye of the future: Unlocking the potential utilization of hydrogels in intraocular lenses.

Hao Wu, Jiale Wang, Wenhui Fan, Qi Zhong, Rongyue Xue, Siyu Li, Zongming Song, Ye Tao

Abstract readReview
In one paragraph

Review in Bioengineering & translational medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hao WuHenan Eye Institute, Henan Eye Hospital, People's Hospital of Zhengzhou University Zhengzhou China.ORCID https://orcid.org/0009-0003-8544-2384
Jiale WangHenan Eye Institute, Henan Eye Hospital, People's Hospital of Zhengzhou University Zhengzhou China.
Wenhui FanHenan Eye Institute, Henan Eye Hospital, People's Hospital of Zhengzhou University Zhengzhou China.
Qi ZhongHenan Eye Institute, Henan Eye Hospital, People's Hospital of Zhengzhou University Zhengzhou China.
Rongyue XueHenan Eye Institute, Henan Eye Hospital, People's Hospital of Zhengzhou University Zhengzhou China.
Siyu LiHenan Eye Institute, Henan Eye Hospital, People's Hospital of Zhengzhou University Zhengzhou China.
Zongming SongHenan Eye Institute, Henan Eye Hospital, People's Hospital of Zhengzhou University Zhengzhou China.
Ye TaoHenan Eye Institute, Henan Eye Hospital, People's Hospital of Zhengzhou University Zhengzhou China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogels are distinguished by their exceptional ability to absorb and retain large volumes of water within their complex three-dimensional polymer networks, which is advantageous for the development of intraocular lenses (IOLs). Their innate hydrophilicity offers an optimal substrate for the fabrication of IOLs that simulate the natural lens' accommodation, thereby reducing irritation and facilitating healing after surgery. The swelling and water retention characteristics of hydrogels contribute to their notable biocompatibility and versatile mechanical properties. However, the clinical application of hydrogels faces challenges, including managing potential adverse postimplantation effects. Rigorous research is essential to ascertain the safety and effectiveness of hydrogels. This review systematically examines the prospects and constraints of hydrogels as innovative materials for IOLs. Our comprehensive analysis examines their inherent properties, various classification strategies, cross-linking processes, and sensitivity to external stimuli. Additionally, we thoroughly evaluate their interactions with ocular tissues, underscoring the potential for hydrogels to be refined into seamless and biologically integrated visual aids. We also discuss the anticipated technological progress and clinical uses of hydrogels in IOL manufacturing. With ongoing technological advancements, the promise of hydrogels is poised to evolve from concept to clinical reality, marking a significant leap forward in ophthalmology characterized by improved patient comfort, enhanced functionality, and reliable safety.

Indexed as

hydrogelintraocular lensesophthalmic applications

Identifiers

PMID39553434
PMCPMC11561835

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.