Evidence map›Paper›PMID 39553379›Full record

ArticleJACC. Advances2024

Cardiovascular Adaptation in Normal Pregnancy With 2D and 3D Echocardiography, Speckle Tracking, and Radial Artery Tonometry.

Tasneem Z Naqvi, Meena Narayanan, Reza Rafie, Salima Qamruddin, Ming-Sum Lee, Marlene E Girardo, Samuel Daneshvar, Songnan Wen, Alice M Stek, Uri Elkayam

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07115199 (Remote Patient Monitoring for Chronic Hypertension During Pregnancy), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07115199 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Remote Patient Monitoring for Chronic Hypertension During Pregnancy (REACH)

TypeinterventionalSponsorRutgers, The State University of New JerseyRan2026 to 2029Enrolled50ConditionsChronic Hypertension in PregnancyArmsRemote Patient Monitoring
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Toward Standardized Cardiac Imaging in Obstetric Care: The Need for Pregnancy-Specific Echocardiographic Reference Values.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2026
    Article
  6. Observational
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Tasneem Z NaqviThe Cardiac Non Invasive Laboratories, Division of Cardiology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Meena NarayananThe Cardiac Non Invasive Laboratories, Division of Cardiology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Reza RafieThe Cardiac Non Invasive Laboratories, Division of Cardiology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Salima QamruddinThe Cardiac Non Invasive Laboratories, Division of Cardiology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Ming-Sum LeeThe Cardiac Non Invasive Laboratories, Division of Cardiology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Marlene E GirardoDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Keck School of Medicine University of Southern California, Los Angeles, California, USA.
Samuel DaneshvarThe Cardiac Non Invasive Laboratories, Division of Cardiology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Songnan WenDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Keck School of Medicine University of Southern California, Los Angeles, California, USA.
Alice M StekDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Keck School of Medicine University of Southern California, Los Angeles, California, USA.
Uri ElkayamThe Cardiac Non Invasive Laboratories, Division of Cardiology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Comprehensive cardiovascular assessment in normal pregnancy using advanced techniques has limited data. Objectives: The aim of the study was to evaluate cardiovascular changes in normal pregnancy using two-dimensional/three-dimensional (3D) echo and applanation tonometry in healthy pregnant women. Methods: Two-dimensional/Doppler, speckle tracking strain, 3D echocardiography, and vascular compliance by applanation tonometry were performed during the first, second, and third trimesters and postpartum. Results: There were 45 healthy women (96% Hispanic) included. The heart rate increased in all trimesters vs postpartum (70.538 ± 9.208 beats/min, 74.878 ± 8.094 beats/min, 74.107 ± 9.231 beats/min vs 61.613 ± 9.790 beats/min, Conclusions: Increased contractility of all four cardiac chambers, LV ejection-duration, and reduced LV afterload provide efficient cardiovascular adaptation despite increased chamber volumes and heart rate during normal pregnancy.

Indexed as

arterial compliancepregnancystrain imagingthree-dimensional echocardiography

Identifiers

PMID39553379
PMCPMC11569893

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.