Evidence map›Paper›PMID 39553217›Full record

ArticleAmerican journal of cancer research2024

Cell-based assay to detect small molecules restoring levels of let-7 miRNAs.

Sirinapa Szewczyk, Brian Buckley, Mikhail Chernov, Xinjiang Wang, Shilpa Pathak, Herman Yeger, Kristopher M Attwood, Renae Holtz, Christine B Ambrosone, Michael J Higgins

Abstract read
In one paragraph

Article in American journal of cancer research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Molecular regulation and therapeutic targeting ofFrontiers in cell and developmental biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sirinapa SzewczykDepartment of Molecular and Cellular Biology, Roswell Park Comprehensive Cancer Center Buffalo, NY 14263, USA.
Brian BuckleyDrug Discovery Core Shared Resource, Roswell Park Comprehensive Cancer Center Buffalo, NY 14263, USA.
Mikhail ChernovDrug Discovery Core Shared Resource, Roswell Park Comprehensive Cancer Center Buffalo, NY 14263, USA.
Xinjiang WangDepartment of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center Buffalo, NY 14263, USA.
Shilpa PathakIQVIA 580 North 4th Street, Columbus, OH 43215, USA.
Herman YegerDepartment of Laboratory Medicine and Pathobiology, University of Toronto Toronto, Ontario M5S 1A8, Canada.
Kristopher M AttwoodDepartment of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center Buffalo, NY 14263, USA.
Renae HoltzDepartment of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center Buffalo, NY 14263, USA.
Christine B AmbrosoneDepartment of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center Buffalo, NY 14263, USA.
Michael J HigginsDepartment of Molecular and Cellular Biology, Roswell Park Comprehensive Cancer Center Buffalo, NY 14263, USA.

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI Dean G. Tang · 1985 to 2026
$116.6M
Relationships between parity, breastfeeding and ER- breast cancer in African American women: Elucidating the biologic underpinnings at the molecular and cellular level.R01CA225947 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI AMBROSONE, CHRISTINE B., HIGGINS, MICHAEL JOSEPH · 2019 to 2023
$3.2M
NCI NIH HHS P30 CA016056NCI NIH HHS R01 CA225947
6 · The paper itself

Abstract

Blockage of

Indexed as

kidneylet-7LIN28BmiRNAmiR-ON systemWilms’ tumor

Identifiers

PMID39553217
PMCPMC11560832

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.