Evidence map›Paper›PMID 39553115›Full record

ArticleCureus2024

Unveiling the Masked Culprit: Central Nervous System Infection With Varicella-Zoster Virus Diagnosed by Multiplex PCR in an Elderly Patient With Atypical Neurological Symptoms.

Takafumi Uchi, Shingo Konno, Natsuki Inoue, Hideo Kihara, Hideki Sugimoto

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Lower lumbar and sacral herpes zoster with central nervous system complications: Two case reports.Dusunen adam : Bakirkoy Ruh ve Sinir Hastaliklari Hastanesi yayin organi · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Takafumi UchiDepartment of Neurology, Toho University Ohashi Medical Center, Tokyo, JPN.
Shingo KonnoDepartment of Neurology, Toho University Ohashi Medical Center, Tokyo, JPN.
Natsuki InoueDepartment of Otolaryngology, Toho University Ohashi Medical Center, Tokyo, JPN.
Hideo KiharaDepartment of Neurology, Toho University Ohashi Medical Center, Tokyo, JPN.
Hideki SugimotoDepartment of Neurology, Toho University Ohashi Medical Center, Tokyo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Varicella-zoster virus (VZV) infections of the central nervous system can be atypical, particularly in elderly patients. Herein, we describe the case of an 80-year-old male presenting with persistent hiccups and dysphagia without the characteristic rash typically associated with VZV infection. Cerebrospinal fluid multiplex polymerase chain reaction (PCR) allowed rapid identification of VZV, thereby enabling the prompt initiation of antiviral therapy. This case underscores the importance of considering VZV in atypical neurological presentations and highlights the utility of multiplex PCR in diagnosing zoster sine herpes, potentially altering the diagnostic approach for similar cases.

Indexed as

central nervous systemdysphagiahiccupsmultiplex-pcr systemvaricella-zoster virus

Identifiers

PMID39553115
PMCPMC11566949

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.