ArticleCureus2024
Spontaneous Cerebrospinal Fluid Rhinorrhea in Pre-operative Pituitary Adenoma: A Report of Two Cases.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Pituitary macroadenomas are neuroendocrine tumors residing in the base of the skull. First-line therapies for prolactin-secreting adenomas (prolactinoma) include medical treatment with dopamine agonists and neurosurgical intervention. Cerebrospinal fluid (CSF) rhinorrhea is a well-known complication following skull base tumor treatment; however, spontaneous CSF rhinorrhea as the initial presenting feature of such tumors is rare. We present two cases of spontaneous CSF rhinorrhea in pre-operative invasive pituitary macroadenomas. Invasive pituitary macroadenomas have the potential to disrupt local skull base structures such as the sellar floor and cavernous sinus. Early warning signs can help aid in prompt diagnosis and successful treatment. Spontaneous CSF rhinorrhea as the initial presenting symptom is rare and may be pivotal in the early diagnosis of pituitary adenomas.
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