Evidence map›Paper›PMID 39553069›Full record

ReviewCureus2024

CRP to Albumin Ratio as a Prognostic Nutrition-Based Biomarker for Patients With Gastric Cancer: A Narrative Review.

Grigorios Christodoulidis, Alexandros Voutyras, George Fotakopoulos, Konstantinos-Eleftherios Koumarelas, Vasiliki E Georgakopoulou, Marina-Nektaria Kouliou, Eirini Sara Agko, Kyriaki Tsagkidou, Dimitra Bartzi, Iraklis Kagkouras and 1 more

Abstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Grigorios ChristodoulidisSurgery, General University Hospital of Larissa, Larissa, GRC.
Alexandros VoutyrasSurgery, General University Hospital of Larissa, Larissa, GRC.
George FotakopoulosNeurosurgery, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Konstantinos-Eleftherios KoumarelasEmergency Medicine, General University Hospital of Larissa, Larissa, GRC.
Vasiliki E GeorgakopoulouPathophysiology and Pulmonology, Laiko General Hospital, Athens, GRC.
Marina-Nektaria KouliouSurgery, General University Hospital of Larissa, Larissa, GRC.
Eirini Sara AgkoIntensive Care Unit, Asklepios Paulinen Klinik Wiesbaden, Wiesbaden, DEU.
Kyriaki TsagkidouGastroenterology, General University Hospital of Larissa, Larissa, GRC.
Dimitra BartziOncology, 251 Air Force General Hospital, Athens, GRC.
Iraklis KagkourasSurgery, Worcestershire Acute Hospitals NHS Trust, Worcester, GBR.
Dimitrios ZacharoulisSurgery, General University Hospital of Larissa, Larissa, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer stands as a significant global health challenge, ranking among the top malignancies worldwide in terms of prevalence and mortality. Despite advances in treatment modalities, including surgical intervention and chemotherapy, its prognosis remains largely unfavorable, with late-stage diagnoses contributing to high mortality rates. In recent years, attention has turned to inflammation-based prognostic markers, notably the CRP to albumin ratio (CAR), as potential indicators of disease progression and patient outcomes postoperatively. The CAR index is observed to have the potential as an independent predictor of survival outcomes, including overall survival (OS), disease-free survival, recurrence-free survival, and cancer-specific survival, but with inconsistent data. Discrepancies in defining optimal CAR cutoff values have been observed, and there are no standardized criteria. CAR is also integrated into the bibliography with other prognostic factors for the development of novel prognostic indices that offer avenues for refining risk stratification and enhancing patient care in gastric cancer management. In this narrative review, we study the utility of the CAR index for the OS of gastric cancer patients after a curative or palliative gastrectomy.

Indexed as

c-reactive protein to albumin ratiocrp/albgastric cancerprognostic biomarkerstomach cancer

Identifiers

PMID39553069
PMCPMC11563776

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.