Evidence map›Paper›PMID 39553057›Full record

ReviewCureus2024

A Comprehensive Review of Recent Trends in Surgical Approaches for Epilepsy Management.

Tara Sabzvari, Muhammed Aflahe Iqbal, Akash Ranganatha, Jean C Daher, Isabel Freire, Syeda Maham Fatima Shamsi, Oriona Vinishia Paul Anthony, Anusha G Hingorani, Aparita S Sinha, Zahra Nazir

Abstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tara SabzvariMedical School, McMaster University, Hamilton, CAN.
Muhammed Aflahe IqbalGeneral Practice, Muslim Educational Society (MES) Medical College Hospital, Perinthalmanna, IND.
Akash RanganathaSurgery, Jagadguru Jayadeva Murugarajendra (JJM) Medical College, Davangere, IND.
Jean C DaherMedicine, Lakeland Regional Health, Lakeland, USA.
Isabel FreireGeneral Practice, Universidad Central del Ecuador, Quito, ECU.
Syeda Maham Fatima ShamsiMedical School, Alfaisal University College of Medicine, Riyadh, SAU.
Oriona Vinishia Paul AnthonySurgery, OO Bogomolets National Medical University, Kyiv, UKR.
Anusha G HingoraniMedicine and Surgery, Mahatma Gandhi Mission (MGM) Medical College and Hospital, Mumbai, IND.
Aparita S SinhaSurgery, Kasturba Medical College, Manipal, Manipal, IND.
Zahra NazirInternal Medicine, Combined Military Hospital, Quetta, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epilepsy is a neurological disorder that affects millions of people worldwide, with a significant proportion of patients experiencing drug-resistant epilepsy, where seizures remain uncontrolled despite medical treatment. This review evaluates the latest surgical techniques for managing epilepsy, focusing on their effectiveness, safety, and the ongoing challenges that hinder their broader adoption. We explored various databases including PubMed, Google Scholar, and Cochrane Library to look for relevant literature using the following keywords: Epilepsy, Resective Surgery, Corpus Collectumy, and Antiepileptic Drugs. A total of 54 relevant articles were found and thoroughly explored. Recent advancements in surgical interventions include resective procedures such as anterior temporal lobectomy, corpus callosotomy, and hemispherectomy, which have been particularly effective in reducing seizures for specific types of epilepsy. Minimally invasive techniques, including laser interstitial thermal therapy and focused ultrasound, are increasingly being used, offering promising outcomes for certain patient groups. Additionally, neuromodulation methods such as deep brain stimulation, vagus nerve stimulation, and responsive neurostimulation provide alternative treatment options, especially for patients who are not suitable candidates for resective surgery. Despite these advancements, the full potential of epilepsy surgery is often underutilized due to various challenges. Inconsistent referral practices, a lack of standardized surgical protocols, and significant socioeconomic barriers continue to limit access to these procedures. Addressing these issues through improved referral processes, better education for healthcare providers and patients, and ensuring equitable access to advanced surgical treatments is crucial for optimizing patient outcomes. Future research should focus on overcoming these barriers and assessing long-term outcomes to further enhance the care of patients with epilepsy.

Indexed as

adult epilepsy surgerydeep brain stimulationdrug-resistant epilepsy (dre)focused ultrasound (fus)laser interstitial thermal therapy (litt)neuromodulationresponsive neurostimulationseizure managementsurgical outcomes researchvagus nerve stimulation

Identifiers

PMID39553057
PMCPMC11568833

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.