Evidence map›Paper›PMID 39552872›Full record

ReviewJournal of thoracic disease2024

Artificial intelligence applications in personalizing lung cancer management: state of the art and future perspectives.

Filippo Lococo, Galal Ghaly, Sara Flamini, Annalisa Campanella, Marco Chiappetta, Emilio Bria, Emanuele Vita, Giampaolo Tortora, Jessica Evangelista, Carolina Sassorossi and 7 more

Abstract readReview
In one paragraph

Review in Journal of thoracic disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Artificial intelligence in respiratory medicine: From diagnosis to treatment and future directions.Chinese medical journal pulmonary and critical care medicine · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Filippo Lococo *Thoracic Surgery Unit, Catholic University of Sacred Heart, Rome, Italy.ORCID https://orcid.org/0000-0002-9383-5554
Galal Ghaly *Thoracic Surgery Unit, Cairo University, Cairo, Egypt.
Sara FlaminiThoracic Surgery Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Annalisa CampanellaThoracic Surgery Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Marco ChiappettaThoracic Surgery Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Emilio BriaMedical Oncology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Emanuele VitaMedical Oncology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Giampaolo TortoraMedical Oncology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Jessica EvangelistaThoracic Surgery Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Carolina SassorossiThoracic Surgery Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Maria Teresa CongedoThoracic Surgery Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Vincenzo ValentiniRadiotherapy Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Evis SalaAdvanced Radiodiagnostic Center, Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy.
Alfredo CesarioOpen Innovation Unit, Scientific Directorate Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Stefano Margaritora *Thoracic Surgery Unit, Catholic University of Sacred Heart, Rome, Italy.
Luca Boldrini *Medical Oncology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Abdelrahman Mohammed *Thoracic Surgery Unit, Cairo University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is still a leading cause of cancer-related deaths worldwide. Vital to ameliorating patient survival rates are early detection, precise evaluation, and personalized treatments. Recent years have witnessed a profound transformation in the field, marked by intricate diagnostic processes and intricate therapeutic protocols that integrate diverse omics domains, heralding a paradigm shift towards personalized and preventive healthcare. This dynamic landscape has embraced the incorporation of advanced machine learning and deep learning techniques, particularly artificial intelligence (AI), into the realm of precision medicine. These groundbreaking innovations create fertile ground for the development of AI-based models adept at extracting valuable insights to inform clinical decisions, with the potential to quantitatively interpret patient data and impact overall patient outcomes significantly. In this comprehensive narrative review, a synthesis of various studies is presented, with a specific focus on three core areas aimed at providing clinicians with a practical understanding of AI-based technologies' potential applications in the diagnosis and management of non-small cell lung cancer (NSCLC). The emphasis is placed on methods for diagnosing malignancy in lung lesions, approaches to predicting histology and other pathological characteristics, and methods for predicting NSCLC gene mutations. The review culminates in a discussion of current trends and future perspectives within the domain of AI-based models, all directed toward enhancing patient care and outcomes in NSCLC. Furthermore, the review underscores the synthesis of diverse studies, accentuating AI applications in NSCLC diagnosis and management. It concludes with a forward-looking discussion on current trends and future perspectives, highlighting the LANTERN Study as a pioneering force set to elevate patient care and outcomes to unprecedented levels.

Indexed as

artificial intelligence (AI)Non-small cell lung cancer (NSCLC)prediction model radiomics

Identifiers

PMID39552872
PMCPMC11565297

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.