Evidence map›Paper›PMID 39552843›Full record

ArticleJournal of thoracic disease2024

The use of electromagnetic navigation bronchoscopy-guided microwave ablation in patients with multiple bilateral pulmonary nodules: a retrospective study of 26 cases.

Siwei Wang, Chi Su, Jing Li, Na Yin, Chunpei Wu, Rong Gao, Shuai Zhang, Xiaojun Wang, Zhenzhong Lin, Dongxue Li and 2 more

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Siwei Wang *Department of Thoracic Surgery, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Nanjing Medical University Affiliated Cancer Hospital & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, China.
Chi Su *Department of Thoracic Surgery, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Nanjing Medical University Affiliated Cancer Hospital & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, China.
Jing Li *Department of Endoscope, Nanjing Medical University Affiliated Cancer Hospital & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, China.
Na YinDepartment of Radiology, Nanjing Medical University Affiliated Cancer Hospital & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, China.
Chunpei WuDepartment of Anesthesiology, Nanjing Medical University Affiliated Cancer Hospital & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, China.
Rong GaoDepartment of Anesthesiology, Nanjing Medical University Affiliated Cancer Hospital & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, China.
Shuai ZhangDepartment of Thoracic Surgery, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Nanjing Medical University Affiliated Cancer Hospital & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, China.
Xiaojun WangDepartment of Thoracic Surgery, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Nanjing Medical University Affiliated Cancer Hospital & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, China.
Zhenzhong LinDepartment of Pathology, Nanjing Medical University Affiliated Cancer Hospital & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, China.
Dongxue LiDepartment of Radiology, Nanjing Medical University Affiliated Cancer Hospital & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, China.
Jingwen Hu *Department of Endoscope, Nanjing Medical University Affiliated Cancer Hospital & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, China.
Ming Li *Department of Thoracic Surgery, Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Nanjing Medical University Affiliated Cancer Hospital & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To treat multiple bilateral ground-glass opacities (GGOs), surgical treatments and electromagnetic navigation bronchoscopy (ENB)-guided ablation therapy are recommended therapeutic measures. However, the differences between bilateral and unilateral ablation, with or without surgery, remain unknown. This study aims to evaluate the differences in efficacy among various strategies. Methods: This retrospective study reports a single-center experience with ENB-guided microwave ablation (MWA) for patients with multiple bilateral GGOs. A total of 26 cases from December 2020 to February 2023 were reviewed. The primary end points were technical safety and efficiency. Results: This study compared three therapeutic strategies for patients with multiple bilateral GGOs based on ENB-guided MWA. Five cases simultaneously underwent video-assisted thoracoscopic surgery (VATS) and ENB-guided MWA, namely simultaneous VATS-MWA group. Eight cases received VATS followed by the second period ENB-guided MWA, namely two-step VATS-MWA group. Thirteen cases were performed with only ENB-guided MWA for bilateral lesions. All conducted treatments were consistent with preoperative assessment. The group of only ENB-guided MWA had the worst pulmonary function and performance status but the highest proportion of pure GGOs. Intriguingly, the use of only ENB-guided MWA showed a favorable performance in pathological detection, while no significant differences were found between the simultaneous VATS-MWA group and the two-step VATS-MWA group. Conclusions: The use of ENB-guided MWA shows efficacy in treating multiple bilateral GGOs suspected of having multiple primary lung cancers. Bilateral ENB-guided MWA is feasible in patients who cannot tolerate surgery, and VATS combined with ENB-guided MWA is safe and can also preserve as much pulmonary function as possible.

Indexed as

bilateral pulmonary nodulesElectromagnetic navigation bronchoscopy (ENB)ground-glass opacities (GGOs)microwave ablation (MWA)

Identifiers

PMID39552843
PMCPMC11565348

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.