Evidence map›Paper›PMID 39552788›Full record

ReviewGenes & diseases2025

Research progress and the prospect of using single-cell sequencing technology to explore the characteristics of the tumor microenvironment.

Wenyige Zhang, Xue Zhang, Feifei Teng, Qijun Yang, Jiayi Wang, Bing Sun, Jie Liu, Jingyan Zhang, Xiaomeng Sun, Hanqing Zhao and 3 more

Abstract readReview
In one paragraph

Review in Genes & diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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  4. Advances in Colorectal Cancer Cell Biology and Clonal Evolution.International journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Wenyige ZhangDepartment of Clinical Laboratory, The 2nd Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi 330006, China.
Xue ZhangQueen Mary College, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi 330006, China.
Feifei TengSchool of Public Health, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi 330006, China.
Qijun YangQueen Mary College, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi 330006, China.
Jiayi WangQueen Mary College, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi 330006, China.
Bing SunQueen Mary College, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi 330006, China.
Jie LiuSchool of Public Health, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi 330006, China.
Jingyan ZhangQueen Mary College, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi 330006, China.
Xiaomeng SunQueen Mary College, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi 330006, China.
Hanqing ZhaoQueen Mary College, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi 330006, China.
Yuxuan XieThe Second Clinical Medical School, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi 330006, China.
Kaili LiaoDepartment of Clinical Laboratory, The 2nd Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi 330006, China.
Xiaozhong WangDepartment of Clinical Laboratory, The 2nd Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi 330006, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In precision cancer therapy, addressing intra-tumor heterogeneity poses a significant obstacle. Due to the heterogeneity of each cell subtype and between cells within the tumor, the sensitivity and resistance of different patients to targeted drugs, chemotherapy,

Indexed as

ApplicationProspectResearch progressSingle-cell sequencingTumor microenvironment

Identifiers

PMID39552788
PMCPMC11566696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.