Evidence map›Paper›PMID 39552745›Full record

ReviewCurrent cardiovascular risk reports2024

Machine Learning in Vascular Medicine: Optimizing Clinical Strategies for Peripheral Artery Disease.

Sean Perez, Sneha Thandra, Ines Mellah, Laura Kraemer, Elsie Ross

Abstract readReview
In one paragraph

Review in Current cardiovascular risk reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sean PerezDepartment of Surgery, University of California San Diego Health, La Jolla, San Diego, CA USA.
Sneha ThandraUniversity of California San Diego School of Medicine, La Jolla, San Diego, CA USA.
Ines MellahUniversity of California San Diego School of Medicine, La Jolla, San Diego, CA USA.
Laura KraemerGeneral Surgery Department, Naval Medical Center San Diego, San Diego, CA USA.
Elsie RossDepartment of Surgery, Division of Vascular and Endovascular Surgery, University of California San Diego Health, 9300 Campus Point Drive #7403, La Jolla, San Diego, CA 92037 USA.

Funding

Artificial Intelligence for early Detection of Peripheral Artery Disease (AID-PAD)R01AG084343 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Elsie Gyang Ross · 2023 to 2026
$2.1M
Using Artificial Intelligence to Enable Early Identification and Treatment of Peripheral Artery DiseaseK01HL148639 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ROSS, ELSIE GYANG · 2019 to 2023
$807k
NHLBI NIH HHS K01 HL148639NIA NIH HHS R01 AG084343
6 · The paper itself

Abstract

Purpose of Review: Peripheral Artery Disease (PAD), a condition affecting millions of patients, is often underdiagnosed due to a lack of symptoms in the early stages and management can be complex given differences in genetic and phenotypic characteristics. This review aims to provide readers with an update on the utility of machine learning (ML) in the management of PAD. Recent Findings: Recent research leveraging electronic health record (EHR) data and ML algorithms have demonstrated significant advances in the potential use of automated systems, namely artificial intelligence (AI), to accurately identify patients who might benefit from further PAD screening. Additionally, deep learning algorithms can be used on imaging data to assist in PAD diagnosis and automate clinical risk stratification.ML models can predict major adverse cardiovascular events (MACE) and major adverse limb events (MALE) with considerable accuracy, with many studies also demonstrating the ability to more accurately risk stratify patients for deleterious outcomes after surgical intervention. These predictions can assist physicians in developing more patient-centric treatment plans and allow for earlier, more aggressive management of modifiable risk-factors in high-risk patients. The use of proteomic biomarkers in ML models offers a valuable addition to traditional screening and stratification paradigms, though clinical utility may be limited by cost and accessibility. Summary: The application of AI to the care of PAD patients may enable earlier diagnosis and more accurate risk stratification, leveraging readily available EHR and imaging data, and there is a burgeoning interest in incorporating biological data for further refinement. Thus, the promise of precision PAD care grows closer. Future research should focus on validating these models via real-world integration into clinical practice and prospective evaluation of the impact of this new care paradigm.

Indexed as

Artificial intelligenceMachine learningPeripheral artery diseasePhenotypingRisk stratification

Identifiers

PMID39552745
PMCPMC11567977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.