Evidence map›Paper›PMID 39552647›Full record

ArticleFrontiers in microbiology2024

Risk factors and clinical prediction models for low-level viremia in people living with HIV receiving antiretroviral therapy: an 11-year retrospective study.

Wenhui Zhang, Jinchuan Shi, Ying Wang, Er Li, Dingyan Yan, Zhongdong Zhang, Mingli Zhu, Jianhua Yu, Yi Wang

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wenhui ZhangDepartment of Infection, Hangzhou Xixi Hospital, Zhejiang Chinese Medical University, Hangzhou, China.
Jinchuan ShiDepartment of Infection, Hangzhou Xixi Hospital, Zhejiang Chinese Medical University, Hangzhou, China.
Ying WangMedical Laboratory, Hangzhou Xixi Hospital, Zhejiang Chinese Medical University, Hangzhou, China.
Er LiDepartment of Nursing, Hangzhou Xixi Hospital, Zhejiang Chinese Medical University, Hangzhou, China.
Dingyan YanDepartment of Infection, Hangzhou Xixi Hospital, Zhejiang Chinese Medical University, Hangzhou, China.
Zhongdong ZhangDepartment of Infection, Hangzhou Xixi Hospital, Zhejiang Chinese Medical University, Hangzhou, China.
Mingli ZhuMedical Laboratory, Hangzhou Xixi Hospital, Zhejiang Chinese Medical University, Hangzhou, China.
Jianhua Yu *Department of Infection, Hangzhou Xixi Hospital, Zhejiang Chinese Medical University, Hangzhou, China.
Yi Wang *Department of Infection, Hangzhou Xixi Hospital, Zhejiang Chinese Medical University, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study explores the risk factors for low-level viremia (LLV) occurrence after ART and develops a risk prediction model. Method: Clinical data and laboratory indicators of people living with HIV (PLWH) at Hangzhou Xixi Hospital from 5 April 2011 to 29 December 2022 were collected. LASSO Cox regression and multivariate Cox regression analysis were performed to identify laboratory indicators and establish a nomogram for predicting LLV occurrence. The nomogram's discrimination and calibration were assessed via ROC curve and calibration plots. The concordance index (C-index) and decision curve analysis (DCA) were used to evaluate its effectiveness. Result: Predictive factors, namely, age, ART delay time, white blood cell (WBC) count, baseline CD4 Conclusion: A simple-to-use nomogram containing 6 routinely detected variables was developed for predicting LLV occurrence in PLWH after ART.

Indexed as

low-level viremianomogrampeople living with HIVprediction modelviral load

Identifiers

PMID39552647
PMCPMC11563986

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.