Evidence map›Paper›PMID 39552561›Full record

ReviewNeurogastroenterology and motility2025

Treatment principles in adults and development of patient-reported outcomes in cyclic vomiting syndrome.

Yaozhu J Chen, Milan Patel, Thangam Venkatesan

Abstract readReview
In one paragraph

Review in Neurogastroenterology and motility, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yaozhu J ChenAstra Zeneca Outcomes Researcher, USA.ORCID https://orcid.org/0000-0003-4552-2294
Milan PatelMedical Student, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Thangam VenkatesanDivision of Gastroenterology, Hepatology and Nutrition, The Ohio State University, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0002-8095-7456

Funding

Third International Symposium on Cyclic Vomiting syndrome and Cannabinoid Hyperemesis SyndromeR13DK135315 · NIDDK · OHIO STATE UNIVERSITY · PI VENKATESAN, THANGAM · 2022 to 2022
$12k
NIDDK NIH HHS R13 DK135315
6 · The paper itself

Abstract

backgroundCyclic vomiting syndrome is a chronic disorder of gut-brain interaction that is present in both adults and children. It is characterized by severe nausea, vomiting, abdominal pain, and several non-GI symptoms. It is also associated with several comorbid conditions such as anxiety and depression, which affect overall health care outcomes.

methodsThis article delineates treatment principles, encompassing both abortive interventions and prophylactic regimens currently recommended for CVS. However, it underscores a critical concern: the absence of FDA-approved medications for CVS treatment, with existing therapies relying on retrospective and open-labeled trials. KEY

resultsThis article emphasizes the pressing need for the development of CVS-specific outcome assessment tools to facilitate more accurate evaluation and robust data collection for the future studies. In exploring this deficiency, the manuscript also presents the up-to-date data and development that enhances our comprehension of patient-centric concepts, and the challenges faced in creating CVS-specific tools, and presents a roadmap for their development. Addressing this gap is crucial for advancing our understanding of CVS and optimizing patient care. CONCLUSIONS AND INFERENCES: This elucidates the current state of CVS management but also advocates for a future where tailored tools enhance our ability to measure and improve the outcomes for individuals with this debilitating disorder.

Indexed as

Patient Reported Outcome MeasuresVomitingAdultHumansclinical outcomescyclic vomitingdisease severitypatient‐reported outcomestreatment

Identifiers

PMID39552561
PMCPMC11911091

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.