Evidence map›Paper›PMID 39552222›Full record

ArticleSoft matter2024

Modeling collagen fibril degradation as a function of matrix microarchitecture.

Bhanjan Debnath, Badri Narayanan Narasimhan, Stephanie I Fraley, Padmini Rangamani

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Soft matter, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Matrix degradation enhances stress relaxation, regulating cell adhesion and spreading.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Bhanjan DebnathDepartment of Mechanical and Aerospace Engineering, University of California San Diego, CA 92093, USA. prangamani@ucsd.edu.ORCID http://orcid.org/0000-0002-3734-8823
Badri Narayanan NarasimhanDepartment of Bioengineering, University of California San Diego, CA 92093, USA. sifraley@ucsd.edu.
Stephanie I FraleyDepartment of Bioengineering, University of California San Diego, CA 92093, USA. sifraley@ucsd.edu.ORCID http://orcid.org/0000-0003-1548-4442
Padmini RangamaniDepartment of Mechanical and Aerospace Engineering, University of California San Diego, CA 92093, USA. prangamani@ucsd.edu.ORCID http://orcid.org/0000-0001-5953-4347

Funding

The Cancer Cell Map Initiative v2.0U54CA274502 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Stephanie Irene Fraley · 2022 to 2026
$14.2M
U of Calif, San Diego Neuroscience Microscopy ImagingP30NS047101 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GLEESON, JOSEPH G, ZHENG, BINHAI · 2003 to 2022
$9.0M
CRCNS: Biophysical modeling of axonal morphology and functionR01MH139350 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Padmini Rangamani · 2024 to 2026
$1.1M
NCI NIH HHS U54 CA274502NIMH NIH HHS R01 MH139350NINDS NIH HHS P30 NS047101
6 · The paper itself

Abstract

Collagenolytic degradation is a process fundamental to tissue remodeling. The microarchitecture of collagen fibril networks changes during development, aging, and disease. Such changes to microarchitecture are often accompanied by changes in matrix degradability. In a matrix, the pore size and fibril characteristics such as length, diameter, number, orientation, and curvature are the major variables that define the microarchitecture.

Indexed as

CollagenExtracellular MatrixModels, BiologicalProteolysisCollagen

Identifiers

PMID39552222
PMCPMC11652085

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.