Evidence map›Paper›PMID 39552145›Full record

ArticleEpidemiology and infection2024

Increased measles and rubella seroprevalence in children using residual blood samples from health facilities and household serosurveys after supplementary immunization activities in two districts in India.

Christine Prosperi, Alvira Z Hasan, Amy K Winter, Itta Krishna Chaaithanya, Neha R Salvi, Sandeep Sharma, Avi Kumar Bansal, Sanjay L Chauhan, Ragini N Kulkarni, Abhishek Lachyan and 20 more

Abstract read
In one paragraph

Article in Epidemiology and infection, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Christine ProsperiInternational Vaccine Access Center, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0003-1942-5319
Alvira Z HasanInternational Vaccine Access Center, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Amy K WinterInternational Vaccine Access Center, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0003-2737-7003
Itta Krishna ChaaithanyaDepartment of Health Research, Model Rural Health Research Unit, Dahanu, Maharashtra, India.
Neha R SalviDepartment of Health Research, Model Rural Health Research Unit, Dahanu, Maharashtra, India.
Sandeep SharmaIndian Council of Medical Research (ICMR)-National JALMA Institute for Leprosy & Other Mycobacterial Diseases, Agra, India.
Avi Kumar BansalIndian Council of Medical Research (ICMR)-National JALMA Institute for Leprosy & Other Mycobacterial Diseases, Agra, India.
Sanjay L ChauhanIndian Council of Medical Research - National Institute for Research in Reproductive and Child Health (NIRRCH), Mumbai, India.
Ragini N KulkarniIndian Council of Medical Research - National Institute for Research in Reproductive and Child Health (NIRRCH), Mumbai, India.
Abhishek LachyanDepartment of Health Research, Model Rural Health Research Unit, Dahanu, Maharashtra, India.
Poonam GawaliDepartment of Health Research, Model Rural Health Research Unit, Dahanu, Maharashtra, India.
Mitali KapoorDepartment of Health Research, Model Rural Health Research Unit, Dahanu, Maharashtra, India.
Arpit Kumar ShrivastavaDepartment of Health Research, Model Rural Health Research Unit, Kanpur, Uttar Pradesh, India.
Saurabh K ChonkerDepartment of Health Research, Model Rural Health Research Unit, Kanpur, Uttar Pradesh, India.
Vaishali BhattDiagnostic Virology Group, Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India.
Ojas KaduskarDiagnostic Virology Group, Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India.
Gururaj Rao DeshpandeDiagnostic Virology Group, Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India.
Ignacio EstebanInternational Vaccine Access Center, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
R SabarinathanIndian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India.
Velusamy Saravana KumarIndian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India.
Shaun A TrueloveInternational Vaccine Access Center, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Muthusamy Santhosh KumarIndian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India.
Jeromie W Vivian ThangarajIndian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India.
Lucky SangalWorld Health Organization, Southeast Asia Region Office, New Delhi, India.
Sanjay M MehendalePD Hinduja Hospital and Medical Research Centre, Mumbai, India.
Gajanan N SapkalDiagnostic Virology Group, Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India.
Nivedita GuptaDivision of Epidemiology and Communicable Diseases, Indian Council of Medical Research, New Delhi, India.
Kyla HayfordInternational Vaccine Access Center, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0002-9872-2313
William J MossInternational Vaccine Access Center, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Manoj V MurhekarIndian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India.

Funding

Bill and Melinda Gates Foundation 1094816World Health Organization 001
6 · The paper itself

Abstract

Residual blood specimens provide a sample repository that could be analyzed to estimate and track changes in seroprevalence with fewer resources than household-based surveys. We conducted parallel facility and community-based cross-sectional serological surveys in two districts in India, Kanpur Nagar District, Uttar Pradesh, and Palghar District, Maharashtra, before and after a measles-rubella supplemental immunization activity (MR-SIA) from 2018 to 2019. Anonymized residual specimens from children 9 months to younger than 15 years of age were collected from public and private diagnostic laboratories and public hospitals and tested for IgG antibodies to measles and rubella viruses. Significant increases in seroprevalence were observed following the MR SIA using the facility-based specimens. Younger children whose specimens were tested at a public facility in Kanpur Nagar District had significantly lower rubella seroprevalence prior to the SIA compared to those attending a private hospital, but this difference was not observed following the SIA. Similar increases in rubella seroprevalence were observed in facility-based and community-based serosurveys following the MR SIA, but trends in measles seroprevalence were inconsistent between the two specimen sources. Despite challenges with representativeness and limited metadata, residual specimens can be useful in estimating seroprevalence and assessing trends through facility-based sentinel surveillance.

Indexed as

Antibodies, ViralMeaslesRubellaAdolescentChildChild, PreschoolCross-Sectional StudiesFamily CharacteristicsFemaleHealth FacilitiesHumansIndiaInfantMaleMeasles virusRubella VaccineAntibodies, ViralRubella Vaccinemeasles (rubeola)rubellaserologyvaccines

Identifiers

PMID39552145
PMCPMC11574605

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.