Evidence map›Paper›PMID 39551899›Full record

ArticleLangenbeck's archives of surgery2024

Back to my future: life after surgery for tertiary hyperparathyroidism.

Riccardo Morandi, Claudio Guarneri, Matteo Nardin, Stefania Maria Filomena Mitola, Nereo Vettoretto, Gianluca Zanni, Elisa Gatta, Guido Alberto Massimo Tiberio, Nazario Portolani, Carlo Cappelli and 1 more

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In one paragraph

Article in Langenbeck's archives of surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Riccardo MorandiDepartment of Clinical and Experimental Sciences, Surgical Clinic, University of Brescia, ASST Spedali Civili, Brescia, Italy. riccardo.morandi@unibs.it.
Claudio GuarneriGeneral Surgery, ASST Spedali Civili Di Brescia PO Montichiari, Brescia, Montichiari, Italy. c.guarneri004@unibs.it.
Matteo NardinInternal Medicine, Department of Medicine, ASST Spedali Civili, Brescia, University of Brescia, Brescia, Italy.
Stefania Maria Filomena MitolaDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Nereo VettorettoGeneral Surgery, ASST Spedali Civili Di Brescia PO Montichiari, Brescia, Montichiari, Italy.
Gianluca ZanniDepartment of Clinical and Experimental Sciences, Surgical Clinic, University of Brescia, ASST Spedali Civili, Brescia, Italy.
Elisa GattaDepartment of Clinical and Experimental Sciences, SSD Endocrinologia, University of Brescia, ASST Spedali Civili, Brescia, Italy.
Guido Alberto Massimo TiberioDepartment of Clinical and Experimental Sciences, Surgical Clinic, University of Brescia, ASST Spedali Civili, Brescia, Italy.
Nazario PortolaniDepartment of Clinical and Experimental Sciences, Surgical Clinic, University of Brescia, ASST Spedali Civili, Brescia, Italy.
Carlo CappelliDepartment of Clinical and Experimental Sciences, SSD Endocrinologia, University of Brescia, ASST Spedali Civili, Brescia, Italy.
Claudio CasellaDepartment of Clinical and Experimental Sciences, Surgical Clinic, University of Brescia, ASST Spedali Civili, Brescia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposesEvaluate the changes in quality of life (QoL) in patients affected by tertiary hyperparathyroidism (THPT) after surgical treatment using the Parathyroidectomy Assessment of Symptoms (PAS) and Short Form-36 (SF-36) questionnaires.

methodsSingle centre longitudinal retrospective, single-institution analysis of 34 patients with THPT and submitted to parathyroidectomy between 2015 and 2021. The PAS and SF-36 questionnaires were administered before surgery and 24 months after discharge.

resultsA significative QoL amelioration was registered in physical SF-36 (42.4 ± 11.7 vs 56.7 ± 9.2; P < 0.001), mental SF-36 (47.3 ± 12.1 vs 61.8 ± 7.9; P < 0.001) and PAS score (582 ± 163 vs 293 ± 141; P < 0.001) with a significative improvement of all the 13 symptoms considered. We found that pre-operative intact parathormone (iPTH) levels, preoperative T-score and time of haemodialysis before RTX were predictors of both PAS and SF-36 mental score modifications. A positive correlation was also fund between pre-operative PAS values and their post operative cutback.

conclusionsParathyroidectomy for THPT brings to a concrete amelioration of all the disease-related and nonspecific symptoms with significative improvement of QoL. To develop a tailored approach of every patient's needs, from diagnosis to future treatment, we suggest to introduce the symptoms assessment scale as standard stage in periodic evaluations.

Indexed as

ParathyroidectomyQuality of LifeAdultAgedFemaleHumansHyperparathyroidismLongitudinal StudiesMaleMiddle AgedRetrospective StudiesSurveys and QuestionnairesTreatment OutcomeParathyroidectomyParathyroidectomy assessment of symptomsQuality of lifeShort Form-36Tertiary hyperparathyroidism

Identifiers

PMID39551899

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.