Evidence map›Paper›PMID 39551897›Full record

ArticleJournal of cancer research and clinical oncology2024

Multi-classification of breast cancer pathology images based on a two-stage hybrid network.

Guolan Wang, Mengjiu Jia, Qichao Zhou, Songrui Xu, Yadong Zhao, Qiaorong Wang, Zhi Tian, Ruyi Shi, Keke Wang, Ting Yan and 2 more

Abstract read
In one paragraph

Article in Journal of cancer research and clinical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Guolan WangSchool of Computer Information Engineering, Shanxi Technology and Business University, Taiyuan, China.
Mengjiu JiaSchool of Computer Information Engineering, Shanxi Technology and Business University, Taiyuan, China.
Qichao ZhouTranslational Medicine Research Center, Shanxi Medical University, Taiyuan, Shanxi, People's Republic of China.
Songrui XuTranslational Medicine Research Center, Shanxi Medical University, Taiyuan, Shanxi, People's Republic of China.
Yadong ZhaoTranslational Medicine Research Center, Shanxi Medical University, Taiyuan, Shanxi, People's Republic of China.
Qiaorong WangTranslational Medicine Research Center, Shanxi Medical University, Taiyuan, Shanxi, People's Republic of China.
Zhi TianSecond Clinical Medical College, Shanxi Medical University, 382 Wuyi Road, Taiyuan, Shanxi, People's Republic of China.
Ruyi ShiDepartment of Cell Biology and Genetics, Shanxi Medical University, Taiyuan, Shanxi, People's Republic of China.
Keke WangThe First Hospital of Shanxi Medical University, Taiyuan, 030001, China.
Ting YanTranslational Medicine Research Center, Shanxi Medical University, Taiyuan, Shanxi, People's Republic of China.
Guohui Chen *Translational Medicine Research Center, Shanxi Medical University, Taiyuan, Shanxi, People's Republic of China. 15343590882@163.com.
Bin Wang *College of Information and Computer, Taiyuan University of Technology, Taiyuan, Shanxi, People's Republic of China. wangbin01@tyut.edu.cn.

Funding

Shanxi Province Higher Education"BillionProject" Science and Technology Guidance Project BYJL027the Central Guidance on Local Science and Technology Development Fund of Shanxi Province YDZJSX2021A018the Fundamental Research Program of Shanxi province 20210302123112the Fundamental Research Program of Shanxi province 20210302123292the Fundamental Research Program of Shanxi province 20210302123293the Funds for International Cooperation and Exchange of Shanxi Province 202304041101034the National Natural Science Foundation of China 62176177the Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi 2023L487the special fund for Science and Technology Innovation Teams of Shanxi Province 202304051001048
6 · The paper itself

Abstract

BACKGROUND AND

objectiveIn current clinical medicine, pathological image diagnosis is the gold standard for cancer diagnosis. After pathologists determine whether breast lesions are malignant or benign, further sub-type classification is often necessary.

methodsFor this task, this study designed a multi-classification model for breast cancer pathological images based on a two-stage hybrid network. Due to limited sample size for breast sub-type data, this study selected the ResNet34 network as the base network and improved it as the first-level convolutional network, using transfer learning to assist network training. In order to compensate for the lack of long-distance dependencies in the convolutional network, the second-level network was designed to use Long Short-Term Memory (LSTM) to capture contextual information in the images for predictive classification.

resultsFor the 8 sub-types of breast cancer classification on the BreakHis (40×, 100×, 200×, 400×) dataset, the ensemble model achieved accuracy rates of 93.67%, 97.08%, 98.01%, and 94.73% respectively. For the 4 sub-types of breast cancer classification on the ICIAR2018 (200×) dataset, the ensemble model achieved accuracy, precision, recall, and F1 Score rates of 93.75%, 92.5%, 92.5%, and 92.5% respectively.

conclusionThe results show that the multi-classification model proposed in this study outperforms other methods in terms of classification performance, and further demonstrate that the proposed RFSAM module is beneficial for improving model performance.

Indexed as

Breast NeoplasmsNeural Networks, ComputerFemaleHumansImage Processing, Computer-AssistedMulti-classificationPathological images of breast cancerTwo-stage hybrid network

Identifiers

PMID39551897
PMCPMC11570553

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.