Evidence map›Paper›PMID 39551894›Full record

ArticleScientific reports2024

In vitro antioxidant, anticancer and in silico studies of polyphenol enriched leaf extract of Asystasia gangetica.

Abhirami Dilkalal, A S Annapurna, T G Umesh

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Abhirami DilkalalDepartment of Botany, Bangalore University, Jnanabharathi, Bengaluru, 560056, India.
A S AnnapurnaDepartment of Botany, Bangalore University, Jnanabharathi, Bengaluru, 560056, India.
T G UmeshDepartment of Botany, Bangalore University, Jnanabharathi, Bengaluru, 560056, India. drtgumesh@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyphenols are natural biomolecules known for circumventing several diseases including cancer with little adverse effects. This study aimed to investigate the polyphenol enriched fractions from the leaf extract of Asystasia gangetica for their composition, biological activities such as antioxidant activity, haemolytic effects, and in vitro cytotoxicity against cancer cell lines. LC-MS/MS analysis of the enriched fractions identified a total of 35 distinct polyphenols with caffeic acid, luteolin, apigenin, and protocatechuic acid at higher concentrations. Fractions AG-3 and AG-4 exhibited the highest total antioxidant activity with higher concentration of phenolics and flavonoids. The AG-4 fraction had the highest levels of DPPH radical scavenging (IC

Indexed as

AntioxidantsPlant ExtractsPlant LeavesPolyphenolsAntineoplastic Agents, PhytogenicApoptosisCell Line, TumorCell ProliferationComputer SimulationHumansMolecular Docking SimulationTandem Mass SpectrometryAntineoplastic Agents, PhytogenicAntioxidantsPlant ExtractsPolyphenolsAntioxidant activityApoptosisAsystasia gangeticaColorectal cancerDockingHaemolysisPolyphenol enrichmentTNIK

Identifiers

PMID39551894
PMCPMC11570673

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.