ArticleBMC urology2024
Multidrug resistance in urinary E. coli higher in males compared to females.
Article in BMC urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Antimicrobial Resistance Trends in Urinary Tract Infections in 6 African Countries.JAMA network open · 2026Article
- Population-Level Uncoupling of Antimicrobial Usage and Resistance in Community-OnsetPathogens (Basel, Switzerland) · 2026Article
- Therapeutic strategies for multi-resistantJAC-antimicrobial resistance · 2026Review
- Uropathogens' AMR in Male and Female Romanian Population-A Bi-Center Analysis over 1 Year.Medicina (Kaunas, Lithuania) · 2026Article
- A national surveillance study on five-year trends in AMR of E. coli from urine samples in Ethiopia.BMC infectious diseases · 2026Article
- Diagnostic tests for urinary tract infections and antimicrobial resistance-a reality check between diagnostic innovation and implementation: a critical narrative review.Frontiers in cellular and infection microbiology · 2026Review
- Determinants of multidrug-resistant urinary tract infections: A retrospective cross-sectional study from a tertiary care hospital in southern Bangladesh.PLOS global public health · 2026Article
- Spatial pattern and risk factors of resistance to important antibiotics amongAntimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Exploring multidrug resistance patterns in community-acquiredAntimicrobial agents and chemotherapy · 2025Article
- Article
- Microbial prevalence and understanding of their antimicrobial susceptibility in urinary tract of patients attending at shar teaching hospital (2018-2022).BMC research notes · 2025Article
- Antimicrobial resistance and beta-lactamase gene distribution among clinical isolates: a two-year cohort study.Scientific reports · 2025Article
- Geo-Temporal Variation in the Antimicrobial Resistance ofAntibiotics (Basel, Switzerland) · 2025Article
- Temporal Trends ofAntibiotics (Basel, Switzerland) · 2025Article
- Comprehensive molecular and phenotypic profiling of uropathogenicFrontiers in microbiology · 2025Article
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundUrinary tract infections (UTIs) are common however the widespread use of antibiotics has led to a rise in antimicrobial resistance (AMR) amongst uropathogens, rendering a significant proportion of infections resistant to first line treatment. AMR in UTIs may differentially affect men and women, younger and older patients. The purpose of this study was to investigate MDR (multi-drug resistance) and AMR in males and females in an Australian health district.
methodsThere were 85,844 E. coli urinary isolates (2007-2020) analysed from adult patients. An E. coli isolate with MDR was defined as resistant to at least 1 agent in ≥ 3 antimicrobial classes. Chi-square tests and relative risk were calculated by comparing resistance in males and females and by age for antibiotics commonly used to treat UTIs in hospital and community collected samples.
resultsThere was a higher proportion of MDR E. coli in males compared to females in both the community (6.4% vs. 5.2%, P < 0.001) and hospital datasets (16.5% vs. 12.8%, P < 0.001). The proportions of MDR for both males and females were significantly higher in the hospital setting. Resistance rates were higher in males compared to females for amoxicillin, amoxicillin/clavulanate, cephalexin and norfloxacin (p < 0.005), though not for trimethoprim. Antibiotic resistance was seen to increase over time.
conclusionsA higher proportion of MDR E. coli were noted in urine samples from males compared with females, possibly due to the increased likelihood of prior treatment for UTIs in men. Antimicrobial stewardship interventions could be targeted towards this cohort to address increasing rates of AMR.
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